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The early days of the HIV-AIDS epidemic in the USA

The work of epidemiologists before the isolation of human immunodeficiency virus 25 years ago demonstrates the power of the epidemiological method to gain an understanding of disease pathogenesis.

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Figure 1: Cluster of AIDS cases for patients linked by sexual contact.

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Jaffe, H. The early days of the HIV-AIDS epidemic in the USA. Nat Immunol 9, 1201–1203 (2008). https://doi.org/10.1038/ni1108-1201

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