Volume 9 Issue 5, May 2006

Volume 9 Issue 5

Defining the connections between various cell types in the mammalian retina remains a major challenge. Li and DeVries show that cone photoreceptors in the ground squirrel form extremely specific connections with different bipolar cell types. These connections may enhance visual acuity and motion sensitivity, and may also contribute to color opponency critical for color vision. The cover image shows the dendritic tree of a b5 bipolar cell reconstructed from serial confocal images. M- and S-cone terminals are outlined in green and blue, respectively. (pp 595 and 669)


Book Review

News and Views

  • News & Views |

    Visual cortex neurons are arranged into maps according to their response selectivity. Ocular dominance and orientation selectivity maps can develop without visual experience. Unexpectedly, the direction selectivity map requires visual input during a critical period, as later visual experience cannot rescue the direction selectivity map in dark-reared ferrets.

    • Frank Sengpiel
  • News & Views |

    Many forms of LTP involve insertion of new postsynaptic AMPA receptors. Plant et al. now report transient insertion of Ca2+-permeable AMPA receptors after LTP induction, and find their activation is required for LTP maintenance.

    • Julie A Kauer
    •  & Robert C Malenka
  • News & Views |

    Defining the connections between the cells of the mammalian retina remains a major challenge. A new study shows how two types of cone photoreceptors selectively connect with the multiple types of postsynaptic bipolar cell.

    • Jonathan B Demb
  • News & Views |

    Orbitofrontal cortex damage impairs decision making. A recent article in Nature shows that this brain region is critical for computing the subjective value of an outcome and using this value signal to make choices

    • Jonathan D Wallis

Brief Communications


Technical Report