Reviews & Analysis

The high platinum loadings at the cathodes of proton exchange membrane fuel cells significantly contribute to the cost of these clean energy conversion devices. Here, the authors critically review and discuss recent developments on low- and non-platinum-based cathode catalysts and catalyst layers.

The number of publicly available proteomics datasets is growing rapidly, but a standardized approach for describing the associated metadata is lacking. Here, the authors propose a format and a software pipeline to present and validate metadata, and integrate them into ProteomeXchange repositories.

Large-scale manufacturing of high-energy Li-ion cells is of paramount importance for developing efficient rechargeable battery systems. Here, the authors report in-depth discussions and evaluations on the use of silicon-containing anodes together with insertion-based cathodes.

The microbiome is becoming recognized as a key determinant of host phenotype. Here, Henry et al. present a framework for building our understanding of how the microbiome also influences host evolution, review empirical examples and research approaches, and highlight emerging questions.

Seed banks are generated when individuals enter a dormant state, a phenomenon that has evolved among diverse taxa, but that is also found in stem cells, brains, and tumors. Here, Lennon et al. synthesize the fundamentals of seed-bank theory and the emergence of complex patterns and dynamics in mathematics and the life sciences.

Vast, ancient impact basins scattered mantle materials across the lunar surface. We review lunar evolution models to identify candidate mantle lithologies, then assess orbital observations to evalutae the current distribution of these materials and implications for fundamental planetary processes.

A key feature of living cells is the cell cycle. In this Perspective, the authors explore attempts to recreate this process and what is still required for an integrated synthetic cell cycle.

Mosquito-borne diseases pose significant global health burdens. In this review, the authors explore Wolbachia and genome engineering approaches to mosquito-borne disease population control.

Many different methods have been developed to forecast climate phenomena like the El Nino-Southern Oscillation (ENSO) which makes a fair comparison of their capabilities crucial. In this perspective, the authors discuss how choices in the evaluation method can lead to an overestimated perceived skill of ENSO forecasts.

The application space for optical fibers is growing, enabled by fibers built using special materials and processes. In this Review, the authors discuss the materials science behind producing crystalline core fibers for diverse applications and progress in the field.

Natural products are an important source of bioactive compounds and have versatile applications in different fields, but their discovery is challenging. Here, the authors review the recent developments in genome mining for discovery of natural products, focusing on compounds from unconventional microorganisms and microbiomes.

Antimicrobial resistance is a growing global problem and low dimensional materials have emerged as a potential solution. Here, the authors review the progress which has been made on low dimensional antimicrobials looking at the materials synthesis, modes of action and currently applications.

Racism thrives in geoscience. We present an antiracism plan to support the recruitment, retention and success of Black, Indigenous, and other people of color in geoscience. Our action plan can be adapted by any organization to remove barriers to participation for all marginalized geoscientists.

This review presents an overview of scenarios where van der Waals (vdW) materials provide unique advantages for nanophotonic biosensing applications. The authors discuss basic sensing principles based on vdW materials, advantages of the reduced dimensionality as well as technological challenges.

Whether or not a city achieves absolute sustainability is difficult to assess with existing frameworks. Here the authors, in a review, show that a further integration of consumption-based accounting and benchmarking is necessary to aid the monitoring and assessment of Sustainable Development Goals in cities.

The ocean supports many livelihoods, but this is currently not sustainable with pressures on the climate and ecosystems. Here, in this perspective, the authors outline the barriers and solutions for financing a sustainable ocean economy.

Effective biological engineering requires the acknowledgement of evolution and its consideration during the design process. In this perspective, the authors present the concept of the evotype to reason about and shape the evolutionary potential of natural and engineered biosystems.

Electrocatalytic nanocarbon (EN) is a class of materials receiving intense interest as next generation electrocatalysts. Although impressive platforms, work is still required to develop our mechanistic understanding of them to that of molecular electrocatalysts.

Improving catalyst performance for ring-opening (co)polymerisation (RO(CO)P) reactions by using heterometallic cooperativity is a promising yet underexplored strategy. Here the authors review advances in heterometallic RO(CO)P catalyst design, highlighting the overarching structure-activity trends and reactivity patterns to inform future catalyst design.