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This study revealed an NF-YB1-SLRL2-bHLH144 regulatory module, centered on a key transcription factor SLRL2, that mediates the ABA-regulated amylose content in rice. Furthermore, SLRL2 is also involved in the regulation of rice dormancy
The researchers present an image sensor that allows every pixel to have independent exposure. It can sample a cell ROI’s fast fluorescence activity with long exposures at different phases, enhancing SNR and temporal resolution for capturing high-speed events.
Type I IFN is vital for antiviral defense. Here, the authors use TurboID-based proximity labeling to comprehensively map the protein landscapes surrounding core IFN signaling members. Among factors uncovered, PJA2 emerged as a negative regulator of IFN signaling that ubiquitinates the Janus kinases.
Urothelial cancer is a challenging disease and an emerging field for targeted therapies. Here, the authors optimize clinical proteomics to provide proteome-level data on tumor specificity and identify robust prognostic subtypes with predictive information for repurposed drug candidates.
Zhao P.J. and his colleagues uncover spatial directionality of urban mobility by using new metrics of anisotropy and centripetality. They find monocentric cities have longer commutes with city expansion, while polycentric cities maintain consistent commuting patterns.
Species-rich communities tend to be less vulnerable to species invasions, but whether this is maintained under environmental stress is unclear. This meta-analysis shows that the positive effect of biodiversity on resistance to invasion in grassland plant communities is reduced by drought but increased by warming and multiple global change factors.
The researchers showcase a silicon-photonics-based analog approach for large-scale image processing that can be deployed for high-speed image compression and de-noising using an auto-encoder framework with minimal power consumption.
Lipid droplet (LD) function relies on protein partitioning between the endoplasmic reticulum (ER) and LD. The authors show that UBXD8 adopts distinct conformations in both membranes and undergoes structural rearrangements during ER-to-LD partitioning.
Precision control of stereochemistry in radical reactions remains a formidable challenge. Here the authors demonstrate an electricity driven asymmetric Lewis acid catalysis to facilitate asymmetric dienylation and allylation reactions, resulting in the formation of all-carbon quaternary stereocenters.
Understanding the physics of charge density waves in emerging superconductors may reveal insights into unconventional superconductivity mechanisms. Here, the authors study the temperature and magnetic-field dependence of charge-density-wave suppression in the unconventional superconductor UTe2.
Pre-satellite era observations of Antarctic glaciers are rare. A unique record of aerial expedition images of East Antarctic outlet glaciers since the 1930s reveal long-term stability and moderate thickening.
This study identifies a decadal link between sea surface temperatures off Western Australia and the western-central tropical Pacific that has emerged since 1985. Driven by external forcings and the rapid changes in the Indo-Pacific warm pool, it may impact future climate.
Multi-scale learning still struggles with imbalanced information and greedy characteristics. Here the authors present MUSE, an Expectation-Maximization-based multi-scale framework, improving predictions across molecular interactions and atomic interfaces.
There are now several van der Waals magnets that have been shown to host skyrmions, however, these are typically hampered by a low Curie temperature, restricting the temperature at which the skyrmions can exist. Here, Zhang, Jiang, Jiang and coauthors find a skyrmion lattice in the van der Waals magnet Fe3 − xGaTe2 above room temperature and demonstrate the critical role of symmetry breaking in crystal lattice in the origin of these skyrmions.
Here, Cottam et al. identify an L-arabinose transporter in Enterohaemorrhagic Escherichia coli and show that metabolism of this dietary sugar upregulates the type 3 secretion system, thus enhancing its fitness within the host gut.
The parabrachial nucleus contains separate populations of neurons that respond to elevated CO2 with EEG arousal and increased breathing. Here we report that the parabrachial respiratory neurons express FoxP2 and are required for respiratory responses to elevated CO2.
How to facilitate the transcription of plant-specific RNA Pol V is largely unknown. Liu et al. find that a conserved RNA Pol II elongator, SPT6L, mediates DNA methylation by its association with Pol V and promoting the production of scaffold RNA.
The authors propose a hydrogen bond modification method to achieve introduction of polarization and enhancement of phase transition temperature in molecular ferroelectrics, exploring the piezoelectric prototype devices of the molecular ferroelectric.
Mimicking high-level abstraction of the brain to achieve energy advantages is a fundamental issue in neuromorphic computing. Here, the authors fabricate an asynchronous chip and demonstrate a high-accuracy neuromorphic system with power consumption of 0.7mW.
Liu et al. developed AI-driven, wearable olfactory interfaces with odor generators for realizing latency-free mixed-reality and fast olfaction recovery. This technology enables personalized olfactory feedback and enhanced virtual environments for various applications including education, and clinical treatment.