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The authors report the measurement of the Little-Parks effect in the unconventional superconductor candidate 4Hb-TaS2. They find a π-shift in the transition-temperature oscillations and an ehancement of Tc as a function of the out-of-plane field when a constant in-plane field is applied, consistent with a multi-component order parameter.
The oxidation of sulfur dioxide to sulfate by hydrogen peroxide in aerosol water significantly impacts global continental regions. Abating oxidants can facilitate the benefit of sulfur dioxide reduction and positive feedback in sulfate mitigation.
Lattice stability related to the structural response is the basis for understanding mechanical and physical behavior of crystalline solids. Here, the authors show a manifestation of elastic instability in high-entropy alloys via elastic strain induced amorphization.
The immunosuppressive tumour microenvironment in Nasopharyngeal carcinoma (NPC) is a cause of low efficacy of immunotherapies in these tumours. In this study, the authors delineate a FLI1-mediated Kyn metabolic mechanism as an immune evasion mechanism in NPC and they show that pharmacological inhibition of FLI1 improves both spontaneous and checkpoint therapy-induced immune responses.
Inflammation promotes insulin resistance in adipocytes, but the mechanism is unclear. Here, the authors show that the inflammatory transcription factor IRF3 drives expression of AIG1, which encodes a hydrolase that breaks down a class of insulin-sensitizing lipid called FAHFAs.
One-dimensional van der Waals heterostructures can realize atomically thin transistor junctions. Here, the authors study electron transfer in such layered structures using ultrafast diffraction and spectroscopy as well as theoretical simulations.
Bacterial chromosomes segregate while undergoing replication. Here the authors show that such concurrent replication and segregation cannot be achieved by passive entropic forces alone, and that loop-extruders could be sufficient to explain segregation.
The study identified and structurally characterized the UDP-glycosyltransferases (UGTs) responsible for regioselective glycosylation of wolfberry-derived bioactive lycibarbarspermidines, elucidating the molecular basis for their substrate specificity.
The authors found that GPi circadian rhythms varied across individuals, with neural activity mainly decreasing at night but sometimes increasing. GPi circadian rhythms were frequency band-dependent and were modulated by the use of extended-release levodopa medication at night.
5′-end capping of pre-mRNA is tightly coupled with the pausing stage of transcription. Here, the authors determine the cryo-EM structures of the paused elongation complex in complex with RNGTT and with both RNGTT and CMTR1.
2D semiconductors may offer a platform for future electronics, but the wafer-scale fabrication of high-performance 2D transistors remains challenging. Here, the authors report a universal all-stacking method to fabricate wafer-scale 2D electronic devices with van der Waals contacts, based on epitaxial metallic electrodes grown on fluorophlogopite mica.
In this study the authors present the Thogoto virus polymerase cryo-EM structures and reveal unique RNA synthesis mechanisms among orthomyxoviruses. RNA synthesis by Thogoto virus polymerase is shown to be weakly dependent on the host factors ANP32A/B/E in human cells in contrast to influenza viruses.
The mechanisms underlying adaptive response to the stress elicited by radiotherapy in glioma cells remains unclear. Here, the authors show that therapeutic ionizing radiation induces rapid genome-wide chromatin reorganization to facilitate P-TEFb-mediated nascent transcriptional induction, which could be targeted to sensitize radiotherapy response in glioma.
The authors reveal a link between the quantum metric and the dielectric constant of insulators, determining the geometric capacitance of insulators and revealing the intrinsic delocalization of electrons in the lattice.
The authors introduce a highspeed acquisition technique, sHAPR, for rapid exploration of biodynamics using fluorescence microscopy. The method leverages sCMOS cameras and custom fibre optics to convert microscopy images into 1D recordings, enabling acquisition at the maximum camera readout rate.
ARID1B, known for its critical role in neuronal development, also performs other functions yet to be fully explored. Here, authors uncover a pivotal function of ARID1B in regulating the quiescence of mesenchymal stem cells by activating non-canonical Activin signaling, providing insight into the link between chromatin remodeling and stem cell state.
This work reveals the presence of the photonic Hall effect and photonic magnetoresistance in a field-dependent random laser. This observation visualizes the influence of magnetic field on random lasers scattering at the microscopic level.
The authors observe THz emission from Ni/Pt heterostructure due to long-range ballistic orbital transport. The velocity of orbital current can be optically tuned by laser fluence, opening the avenue for future optorbitronic devices.
Chirality has long fascinated chemists, but asymmetric synthesis has largely focused on central, axial, and helical chirality to date. Here, the authors synthesize dianthranilides with planar chirality, via cinchona alkaloid-catalyzed (dynamic) kinetic resolution.
By resonant pumping the organic cation in 2D perovskite, Fu et al. report the electronic and mechanical couplings between the organic and inorganic sublattices, evidenced by the reduced bandgap and modified lattice degree of freedom within the inorganic sublattice, and slow heat transfer process.