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Eiji Hara is a professor at the Research Institute for Microbial Diseases, Osaka University, Japan. Eiji recalls the discovery of the basis for the irreversibility of cellular senescence, published in Nature Cell Biology in 2006.
Pietro De Camilli is a professor of neuroscience and of cell biology at Yale University, CT, as well as an investigator in the Howard Hughes Medical Institute. Pietro discusses how his group’s 1999 Nature Cell Biology study linking amphiphysin with dynamin in clathrin-mediated endocytosis came to be.
Huck-Hui Ng is a senior group leader at the Genome Institute of Singapore of A*STAR. In this article, Ng revisits the 2009 Nature Cell Biology study in which he and his team described the role of Esrrb in somatic cell reprogramming.
Sarah Teichmann, head of cellular genetics at the Wellcome Sanger Institute, reflects on the dawn of the single-cell genomics era and a pivotal decision that changed the course of her career.
Maria Antonietta (Antonella) De Matteis is a professor of biology at the University of Naples Federico II and leads the cell biology programme at the Telethon Institute of Genetics and Medicine in Pozzuoli, Italy. Antonella recalls the beginning of her research program on phosphatidylinositol 4-phosphate (PI4P) at the Golgi, published in our pages in 1999 and 2004.
Danfeng Cai, an assistant professor in the Department of Biochemistry and Molecular Biology at the Johns Hopkins Bloomberg School of Public Health, discusses her career path, including her work on the biomolecular condensation of YAP, and her excitement in her ongoing work on transcriptional condensates.