Volume 39

  • No. 4 April 2021

    A catalog of Earth’s microbiomes

    Illustration showing the completion of a genomic catalog of Earth’s microbiomes. Nayfach et al. apply metagenomics to more than ten thousand samples from diverse habitats, extending the known phylogenetic diversity of bacteria and archaea.

    See Nayfach et al.

  • No. 3 March 2021

    Nature Biotechnologycelebrates its 25th anniversary

    Nature Biotechnology celebrates 25 years of publishing the very best of biotech science and business.

    See Editorial

  • No. 2 February 2021

    How pain receptors drive inflammation

    Colorized scanning electron micrograph of silicone-encapsulated gold interconnects of a device for epineural optogenetic neuromodulation. Michoud et al. use the device to show how nociceptor activation drives protective pain behavior and inflammation.

    See Michoud et al.

  • No. 1 January 2021

    Resilient off-the-shelf T cells

    Colored scanning electron micrograph of resting human T lymphocytes. Mo et al. present an alloimmune defense receptor that allows allogeneic T cells to resist rejection by the host immune system by deleting activated host T and NK cells.

    See Mo et al.