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The need for a public proteomics repository

Nature Biotechnology volume 22, pages 471–472 (2004)Cite this article

Large-scale protein expression measurements promise to open exciting areas of research, ranging from systematic investigations of post-transcriptional regulation, to numerical models of protein synthesis and decay, to detailed functional analyses of the many proteins expressed by a cell. This promise is even greater when such protein expression data are combined with DNA microarray or protein interaction data—such combinations offer the tantalizing promise of quantitative models of cellular events. Unfortunately, the field of proteomics has been slow to embrace one of the most important lessons from DNA microarrays: open availability of raw data. The availability of DNA microarray data, coupled with public genome sequence data, is arguably one of the primary forces driving computational research in functional genomics.

A shortage of public data

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Authors and Affiliations

  1. Center for Systems and Synthetic Biology & Institute for Cellular & Molecular Biology, University of Texas at Austin, Austin, 78712, Texas, USA

    John T Prince, Mark W Carlson, Rong Wang, Peng Lu & Edward M Marcotte

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  1. John T Prince
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  2. Mark W Carlson
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  3. Rong Wang
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  4. Peng Lu
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  5. Edward M Marcotte
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Correspondence to Edward M Marcotte.

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Prince, J., Carlson, M., Wang, R. et al. The need for a public proteomics repository. Nat Biotechnol 22, 471–472 (2004). https://doi.org/10.1038/nbt0404-471

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