Volume 577 Issue 7789, 9 January 2020

Unequal opportunities

Nutrition is a key determinant of childhood morbidity and mortality. Similarly, educational attainment is a critical determinant of child health. In this week’s issue, Simon Hay and his colleagues present two papers that offer high-resolution subnational mapping of child growth failure and educational attainment between 2000 and 2017 for around a hundred low- and middle-income countries, from Africa to the Middle East, Asia and South America. The researchers find that although there has been significant progress in both areas, considerable geographical inequalities remain in many countries. Although child potential is everywhere, opportunity is not.

Cover image: Anthony Asael/Art in all of Us/Getty

This Week

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    News & Views

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  • Reviews

  • Review Article |

    This Review describes progress in the study of human genetics, in which rapid advances in technology, foundational genomic resources and analytical tools have contributed to the understanding of the mechanisms responsible for many rare and common diseases and to preventative and therapeutic strategies for many of these conditions.

    • Melina Claussnitzer
    • , Judy H. Cho
    • , Rory Collins
    • , Nancy J. Cox
    • , Emmanouil T. Dermitzakis
    • , Matthew E. Hurles
    • , Sekar Kathiresan
    • , Eimear E. Kenny
    • , Cecilia M. Lindgren
    • , Daniel G. MacArthur
    • , Kathryn N. North
    • , Sharon E. Plon
    • , Heidi L. Rehm
    • , Neil Risch
    • , Charles N. Rotimi
    • , Jay Shendure
    • , Nicole Soranzo
    •  & Mark I. McCarthy

    Collection:

  • Articles

  • Article |

    Only one repeating fast radio burst has been localized, to an irregular dwarf galaxy; now another is found to come from a star-forming region of a nearby spiral galaxy.

    • B. Marcote
    • , K. Nimmo
    • , J. W. T. Hessels
    • , S. P. Tendulkar
    • , C. G. Bassa
    • , Z. Paragi
    • , A. Keimpema
    • , M. Bhardwaj
    • , R. Karuppusamy
    • , V. M. Kaspi
    • , C. J. Law
    • , D. Michilli
    • , K. Aggarwal
    • , B. Andersen
    • , A. M. Archibald
    • , K. Bandura
    • , G. C. Bower
    • , P. J. Boyle
    • , C. Brar
    • , S. Burke-Spolaor
    • , B. J. Butler
    • , T. Cassanelli
    • , P. Chawla
    • , P. Demorest
    • , M. Dobbs
    • , E. Fonseca
    • , U. Giri
    • , D. C. Good
    • , K. Gourdji
    • , A. Josephy
    • , A. Yu. Kirichenko
    • , F. Kirsten
    • , T. L. Landecker
    • , D. Lang
    • , T. J. W. Lazio
    • , D. Z. Li
    • , H.-H. Lin
    • , J. D. Linford
    • , K. Masui
    • , J. Mena-Parra
    • , A. Naidu
    • , C. Ng
    • , C. Patel
    • , U.-L. Pen
    • , Z. Pleunis
    • , M. Rafiei-Ravandi
    • , M. Rahman
    • , A. Renard
    • , P. Scholz
    • , S. R. Siegel
    • , K. M. Smith
    • , I. H. Stairs
    • , K. Vanderlinde
    •  & A. V. Zwaniga
  • Article |

    Microwave-mediated coupling of electron spins separated by more than 4 mm is demonstrated, suggesting the possibility of using photons at microwave frequencies to create long-range two-qubit gates between distant spins.

    • F. Borjans
    • , X. G. Croot
    • , X. Mi
    • , M. J. Gullans
    •  & J. R. Petta
  • Article |

    The synthesis of surprisingly stable, free-standing single layers of amorphous carbon and their analysis by atomic-resolution imaging could settle a debate about their atomic arrangement and offer unusual electronics applications.

    • Chee-Tat Toh
    • , Hongji Zhang
    • , Junhao Lin
    • , Alexander S. Mayorov
    • , Yun-Peng Wang
    • , Carlo M. Orofeo
    • , Darim Badur Ferry
    • , Henrik Andersen
    • , Nurbek Kakenov
    • , Zenglong Guo
    • , Irfan Haider Abidi
    • , Hunter Sims
    • , Kazu Suenaga
    • , Sokrates T. Pantelides
    •  & Barbaros Özyilmaz
  • Article |

    A growth process in which protons decouple graphene from the underlying substrate greatly reduces the number of wrinkles that usually degrade large graphene films grown by chemical vapour deposition.

    • Guowen Yuan
    • , Dongjing Lin
    • , Yong Wang
    • , Xianlei Huang
    • , Wang Chen
    • , Xuedong Xie
    • , Junyu Zong
    • , Qian-Qian Yuan
    • , Hang Zheng
    • , Di Wang
    • , Jie Xu
    • , Shao-Chun Li
    • , Yi Zhang
    • , Jian Sun
    • , Xiaoxiang Xi
    •  & Libo Gao
  • Article |

    A method of deposition of mixed-cation hybrid perovskite films as lattice-mismatched substrates for an α-FAPbI3 film is described, giving strains of up to 2.4 per cent while also stabilizing the metastable α-FAPbI3 phase for several hundred days.

    • Yimu Chen
    • , Yusheng Lei
    • , Yuheng Li
    • , Yugang Yu
    • , Jinze Cai
    • , Ming-Hui Chiu
    • , Rahul Rao
    • , Yue Gu
    • , Chunfeng Wang
    • , Woojin Choi
    • , Hongjie Hu
    • , Chonghe Wang
    • , Yang Li
    • , Jiawei Song
    • , Jingxin Zhang
    • , Baiyan Qi
    • , Muyang Lin
    • , Zhuorui Zhang
    • , Ahmad E. Islam
    • , Benji Maruyama
    • , Shadi Dayeh
    • , Lain-Jong Li
    • , Kesong Yang
    • , Yu-Hwa Lo
    •  & Sheng Xu
  • Article |

    A random heteropolymer based on four monomers can facilitate proton transport across lipid bilayers almost as rapidly as natural ion channels and with high selectivity over other ions.

    • Tao Jiang
    • , Aaron Hall
    • , Marco Eres
    • , Zahra Hemmatian
    • , Baofu Qiao
    • , Yun Zhou
    • , Zhiyuan Ruan
    • , Andrew D. Couse
    • , William T. Heller
    • , Haiyan Huang
    • , Monica Olvera de la Cruz
    • , Marco Rolandi
    •  & Ting Xu
  • Article |

    A reconstruction of permafrost dynamics using speleothems from a Siberian cave indicates that Siberian permafrost is robust to warming when Arctic sea ice is present, but vulnerable when it is absent.

    • A. Vaks
    • , A. J. Mason
    • , S. F. M. Breitenbach
    • , A. M. Kononov
    • , A. V. Osinzev
    • , M. Rosensaft
    • , A. Borshevsky
    • , O. S. Gutareva
    •  & G. M. Henderson
  • Article |

    The potential for infinite persistence of planktonic predator and prey cycles is experimentally demonstrated and these cycles show resilience in the presence of stochastic events.

    • Bernd Blasius
    • , Lars Rudolf
    • , Guntram Weithoff
    • , Ursula Gaedke
    •  & Gregor F. Fussmann
  • Article | | Open Access

    High-resolution subnational mapping of child growth failure indicators for 105 low- and middle-income countries between 2000 and 2017 shows that, despite considerable progress, substantial geographical inequalities still exist in some countries.

    • Damaris K. Kinyoki
    • , Aaron E. Osgood-Zimmerman
    • , Brandon V. Pickering
    • , Lauren E. Schaeffer
    • , Laurie B. Marczak
    • , Alice Lazzar-Atwood
    • , Michael L. Collison
    • , Nathaniel J. Henry
    • , Zegeye Abebe
    • , Abdu A. Adamu
    • , Victor Adekanmbi
    • , Keivan Ahmadi
    • , Olufemi Ajumobi
    • , Ayman Al-Eyadhy
    • , Rajaa M. Al-Raddadi
    • , Fares Alahdab
    • , Mehran Alijanzadeh
    • , Vahid Alipour
    • , Khalid Altirkawi
    • , Saeed Amini
    • , Catalina Liliana Andrei
    • , Carl Abelardo T. Antonio
    • , Jalal Arabloo
    • , Olatunde Aremu
    • , Mehran Asadi-Aliabadi
    • , Suleman Atique
    • , Marcel Ausloos
    • , Marco Avila
    • , Ashish Awasthi
    • , Beatriz Paulina Ayala Quintanilla
    • , Samad Azari
    • , Alaa Badawi
    • , Till Winfried Bärnighausen
    • , Quique Bassat
    • , Kaleab Baye
    • , Neeraj Bedi
    • , Bayu Begashaw Bekele
    • , Michelle L. Bell
    • , Natalia V. Bhattacharjee
    • , Krittika Bhattacharyya
    • , Suraj Bhattarai
    • , Zulfiqar A. Bhutta
    • , Belete Biadgo
    • , Boris Bikbov
    • , Andrey Nikolaevich Briko
    • , Gabrielle Britton
    • , Roy Burstein
    • , Zahid A. Butt
    • , Josip Car
    • , Carlos A. Castañeda-Orjuela
    • , Franz Castro
    • , Ester Cerin
    • , Michael G. Chipeta
    • , Dinh-Toi Chu
    • , Michael A. Cork
    • , Elizabeth A. Cromwell
    • , Lucía Cuevas-Nasu
    • , Lalit Dandona
    • , Rakhi Dandona
    • , Farah Daoud
    • , Rajat Das Gupta
    • , Nicole Davis Weaver
    • , Diego De Leo
    • , Jan-Walter De Neve
    • , Kebede Deribe
    • , Beruk Berhanu Desalegn
    • , Aniruddha Deshpande
    • , Melaku Desta
    • , Daniel Diaz
    • , Mesfin Tadese Dinberu
    • , David Teye Doku
    • , Manisha Dubey
    • , Andre R. Durães
    • , Laura Dwyer-Lindgren
    • , Lucas Earl
    • , Andem Effiong
    • , Maysaa El Sayed Zaki
    • , Maha El Tantawi
    • , Ziad El-Khatib
    • , Babak Eshrati
    • , Mohammad Fareed
    • , Andre Faro
    • , Seyed-Mohammad Fereshtehnejad
    • , Irina Filip
    • , Florian Fischer
    • , Nataliya A. Foigt
    • , Morenike Oluwatoyin Folayan
    • , Takeshi Fukumoto
    • , Tsegaye Tewelde Gebrehiwot
    • , Kebede Embaye Gezae
    • , Alireza Ghajar
    • , Paramjit Singh Gill
    • , Philimon N. Gona
    • , Sameer Vali Gopalani
    • , Ayman Grada
    • , Yuming Guo
    • , Arvin Haj-Mirzaian
    • , Arya Haj-Mirzaian
    • , Jason B. Hall
    • , Samer Hamidi
    • , Andualem Henok
    • , Bernardo Hernández Prado
    • , Mario Herrero
    • , Claudiu Herteliu
    • , Chi Linh Hoang
    • , Michael K. Hole
    • , Naznin Hossain
    • , Mehdi Hosseinzadeh
    • , Guoqing Hu
    • , Sheikh Mohammed Shariful Islam
    • , Mihajlo Jakovljevic
    • , Ravi Prakash Jha
    • , Jost B. Jonas
    • , Jacek Jerzy Jozwiak
    • , Amaha Kahsay
    • , Tanuj Kanchan
    • , Manoochehr Karami
    • , Amir Kasaeian
    • , Yousef Saleh Khader
    • , Ejaz Ahmad Khan
    • , Mona M. Khater
    • , Yun Jin Kim
    • , Ruth W. Kimokoti
    • , Adnan Kisa
    • , Sonali Kochhar
    • , Soewarta Kosen
    • , Ai Koyanagi
    • , Kewal Krishan
    • , Barthelemy Kuate Defo
    • , G. Anil Kumar
    • , Manasi Kumar
    • , Sheetal D. Lad
    • , Faris Hasan Lami
    • , Paul H. Lee
    • , Aubrey J. Levine
    • , Shanshan Li
    • , Shai Linn
    • , Rakesh Lodha
    • , Hassan Magdy Abd El Razek
    • , Muhammed Magdy Abd El Razek
    • , Marek Majdan
    • , Azeem Majeed
    • , Reza Malekzadeh
    • , Deborah Carvalho Malta
    • , Abdullah A. Mamun
    • , Mohammad Ali Mansournia
    • , Francisco Rogerlândio Martins-Melo
    • , Anthony Masaka
    • , Benjamin Ballard Massenburg
    • , Benjamin K. Mayala
    • , Fabiola Mejia-Rodriguez
    • , Mulugeta Melku
    • , Walter Mendoza
    • , George A. Mensah
    • , Tomasz Miazgowski
    • , Ted R. Miller
    • , G. K. Mini
    • , Erkin M. Mirrakhimov
    • , Babak Moazen
    • , Aso Mohammad Darwesh
    • , Shafiu Mohammed
    • , Farnam Mohebi
    • , Ali H. Mokdad
    • , Yoshan Moodley
    • , Ghobad Moradi
    • , Maziar Moradi-Lakeh
    • , Paula Moraga
    • , Shane Douglas Morrison
    • , Jonathan F. Mosser
    • , Seyyed Meysam Mousavi
    • , Ulrich Otto Mueller
    • , Christopher J. L. Murray
    • , Ghulam Mustafa
    • , Mehdi Naderi
    • , Mohsen Naghavi
    • , Farid Najafi
    • , Vinay Nangia
    • , Duduzile Edith Ndwandwe
    • , Ionut Negoi
    • , Josephine W. Ngunjiri
    • , Huong Lan Thi Nguyen
    • , Long Hoang Nguyen
    • , Son Hoang Nguyen
    • , Jing Nie
    • , Chukwudi A. Nnaji
    • , Jean Jacques Noubiap
    • , Malihe Nourollahpour Shiadeh
    • , Peter S. Nyasulu
    • , Felix Akpojene Ogbo
    • , Andrew T. Olagunju
    • , Bolajoko Olubukunola Olusanya
    • , Jacob Olusegun Olusanya
    • , Eduardo Ortiz-Panozo
    • , Stanislav S. Otstavnov
    • , Mahesh P. A.
    • , Adrian Pana
    • , Anamika Pandey
    • , Sanghamitra Pati
    • , Snehal T. Patil
    • , George C. Patton
    • , Norberto Perico
    • , David M. Pigott
    • , Meghdad Pirsaheb
    • , Ellen G. Piwoz
    • , Maarten J. Postma
    • , Akram Pourshams
    • , Swayam Prakash
    • , Hedley Quintana
    • , Amir Radfar
    • , Alireza Rafiei
    • , Vafa Rahimi-Movaghar
    • , Rajesh Kumar Rai
    • , Fatemeh Rajati
    • , David Laith Rawaf
    • , Salman Rawaf
    • , Rahul Rawat
    • , Giuseppe Remuzzi
    • , Andre M. N. Renzaho
    • , Carlos Rios-González
    • , Leonardo Roever
    • , Jennifer M. Ross
    • , Ali Rostami
    • , Nafis Sadat
    • , Yahya Safari
    • , Mahdi Safdarian
    • , Amirhossein Sahebkar
    • , Nasir Salam
    • , Payman Salamati
    • , Yahya Salimi
    • , Hamideh Salimzadeh
    • , Abdallah M. Samy
    • , Benn Sartorius
    • , Brijesh Sathian
    • , Megan F. Schipp
    • , David C. Schwebel
    • , Anbissa Muleta Senbeta
    • , Sadaf G. Sepanlou
    • , Masood Ali Shaikh
    • , Teresa Shamah Levy
    • , Mohammadbagher Shamsi
    • , Kiomars Sharafi
    • , Rajesh Sharma
    • , Aziz Sheikh
    • , Apurba Shil
    • , Diego Augusto Santos Silva
    • , Jasvinder A. Singh
    • , Dhirendra Narain Sinha
    • , Moslem Soofi
    • , Agus Sudaryanto
    • , Mu’awiyyah Babale Sufiyan
    • , Rafael Tabarés-Seisdedos
    • , Birkneh Tilahun Tadesse
    • , Mohamad-Hani Temsah
    • , Abdullah Sulieman Terkawi
    • , Zemenu Tadesse Tessema
    • , Andrew L. Thorne-Lyman
    • , Marcos Roberto Tovani-Palone
    • , Bach Xuan Tran
    • , Khanh Bao Tran
    • , Irfan Ullah
    • , Olalekan A. Uthman
    • , Masoud Vaezghasemi
    • , Afsane Vaezi
    • , Pascual R. Valdez
    • , John Vanderheide
    • , Yousef Veisani
    • , Francesco S. Violante
    • , Vasily Vlassov
    • , Giang Thu Vu
    • , Linh Gia Vu
    • , Yasir Waheed
    • , Judd L. Walson
    • , Yafeng Wang
    • , Yuan-Pang Wang
    • , Elizabeth N. Wangia
    • , Andrea Werdecker
    • , Gelin Xu
    • , Tomohide Yamada
    • , Engida Yisma
    • , Naohiro Yonemoto
    • , Mustafa Z. Younis
    • , Mahmoud Yousefifard
    • , Chuanhua Yu
    • , Sojib Bin Zaman
    • , Mohammad Zamani
    • , Yunquan Zhang
    • , Nicholas J. Kassebaum
    •  & Simon I. Hay
  • Article | | Open Access

    Analyses of the proportions of individuals who have completed key levels of schooling across all low- and middle-income countries from 2000 to 2017 reveal inequalities across countries as well as within populations.

    • Nicholas Graetz
    • , Lauren Woyczynski
    • , Katherine F. Wilson
    • , Jason B. Hall
    • , Kalkidan Hassen Abate
    • , Foad Abd-Allah
    • , Oladimeji M. Adebayo
    • , Victor Adekanmbi
    • , Mahdi Afshari
    • , Olufemi Ajumobi
    • , Tomi Akinyemiju
    • , Fares Alahdab
    • , Ziyad Al-Aly
    • , Jacqueline Elizabeth Alcalde Rabanal
    • , Mehran Alijanzadeh
    • , Vahid Alipour
    • , Khalid Altirkawi
    • , Mohammadreza Amiresmaili
    • , Nahla Hamed Anber
    • , Catalina Liliana Andrei
    • , Mina Anjomshoa
    • , Carl Abelardo T. Antonio
    • , Jalal Arabloo
    • , Olatunde Aremu
    • , Krishna K. Aryal
    • , Mehran Asadi-Aliabadi
    • , Suleman Atique
    • , Marcel Ausloos
    • , Ashish Awasthi
    • , Beatriz Paulina Ayala Quintanilla
    • , Samad Azari
    • , Alaa Badawi
    • , Joseph Adel Mattar Banoub
    • , Suzanne Lyn Barker-Collo
    • , Anthony Barnett
    • , Neeraj Bedi
    • , Derrick A. Bennett
    • , Natalia V. Bhattacharjee
    • , Krittika Bhattacharyya
    • , Suraj Bhattarai
    • , Zulfiqar A. Bhutta
    • , Ali Bijani
    • , Boris Bikbov
    • , Gabrielle Britton
    • , Roy Burstein
    • , Zahid A. Butt
    • , Rosario Cárdenas
    • , Félix Carvalho
    • , Carlos A. Castañeda-Orjuela
    • , Franz Castro
    • , Ester Cerin
    • , Jung-Chen Chang
    • , Michael L. Collison
    • , Cyrus Cooper
    • , Michael A. Cork
    • , Farah Daoud
    • , Rajat Das Gupta
    • , Nicole Davis Weaver
    • , Jan-Walter De Neve
    • , Kebede Deribe
    • , Beruk Berhanu Desalegn
    • , Aniruddha Deshpande
    • , Melaku Desta
    • , Meghnath Dhimal
    • , Daniel Diaz
    • , Mesfin Tadese Dinberu
    • , Shirin Djalalinia
    • , Manisha Dubey
    • , Eleonora Dubljanin
    • , Andre R. Durães
    • , Laura Dwyer-Lindgren
    • , Lucas Earl
    • , Mohammad Ebrahimi Kalan
    • , Ziad El-Khatib
    • , Babak Eshrati
    • , Mahbobeh Faramarzi
    • , Mohammad Fareed
    • , Andre Faro
    • , Seyed-Mohammad Fereshtehnejad
    • , Eduarda Fernandes
    • , Irina Filip
    • , Florian Fischer
    • , Takeshi Fukumoto
    • , Jose A. García
    • , Paramjit Singh Gill
    • , Tiffany K. Gill
    • , Philimon N. Gona
    • , Sameer Vali Gopalani
    • , Ayman Grada
    • , Yuming Guo
    • , Rajeev Gupta
    • , Vipin Gupta
    • , Arvin Haj-Mirzaian
    • , Arya Haj-Mirzaian
    • , Randah R. Hamadeh
    • , Samer Hamidi
    • , Mehedi Hasan
    • , Hamid Yimam Hassen
    • , Delia Hendrie
    • , Andualem Henok
    • , Nathaniel J. Henry
    • , Bernardo Hernández Prado
    • , Claudiu Herteliu
    • , Michael K. Hole
    • , Naznin Hossain
    • , Mehdi Hosseinzadeh
    • , Guoqing Hu
    • , Olayinka Stephen Ilesanmi
    • , Seyed Sina Naghibi Irvani
    • , Sheikh Mohammed Shariful Islam
    • , Neda Izadi
    • , Mihajlo Jakovljevic
    • , Ravi Prakash Jha
    • , John S. Ji
    • , Jost B. Jonas
    • , Zahra Jorjoran Shushtari
    • , Jacek Jerzy Jozwiak
    • , Tanuj Kanchan
    • , Amir Kasaeian
    • , Ali Kazemi Karyani
    • , Peter Njenga Keiyoro
    • , Chandrasekharan Nair Kesavachandran
    • , Yousef Saleh Khader
    • , Morteza Abdullatif Khafaie
    • , Ejaz Ahmad Khan
    • , Mona M. Khater
    • , Aliasghar A. Kiadaliri
    • , Daniel N. Kiirithio
    • , Yun Jin Kim
    • , Ruth W. Kimokoti
    • , Damaris K. Kinyoki
    • , Adnan Kisa
    • , Soewarta Kosen
    • , Ai Koyanagi
    • , Kewal Krishan
    • , Barthelemy Kuate Defo
    • , Manasi Kumar
    • , Pushpendra Kumar
    • , Faris Hasan Lami
    • , Paul H. Lee
    • , Aubrey J. Levine
    • , Shanshan Li
    • , Yu Liao
    • , Lee-Ling Lim
    • , Stefan Listl
    • , Jaifred Christian F. Lopez
    • , Marek Majdan
    • , Reza Majdzadeh
    • , Azeem Majeed
    • , Reza Malekzadeh
    • , Mohammad Ali Mansournia
    • , Francisco Rogerlândio Martins-Melo
    • , Anthony Masaka
    • , Benjamin Ballard Massenburg
    • , Benjamin K. Mayala
    • , Kala M. Mehta
    • , Walter Mendoza
    • , George A. Mensah
    • , Tuomo J. Meretoja
    • , Tomislav Mestrovic
    • , Ted R. Miller
    • , G. K. Mini
    • , Erkin M. Mirrakhimov
    • , Babak Moazen
    • , Dara K. Mohammad
    • , Aso Mohammad Darwesh
    • , Shafiu Mohammed
    • , Farnam Mohebi
    • , Ali H. Mokdad
    • , Lorenzo Monasta
    • , Yoshan Moodley
    • , Mahmood Moosazadeh
    • , Ghobad Moradi
    • , Maziar Moradi-Lakeh
    • , Paula Moraga
    • , Lidia Morawska
    • , Shane Douglas Morrison
    • , Jonathan F. Mosser
    • , Seyyed Meysam Mousavi
    • , Christopher J. L. Murray
    • , Ghulam Mustafa
    • , Azin Nahvijou
    • , Farid Najafi
    • , Vinay Nangia
    • , Duduzile Edith Ndwandwe
    • , Ionut Negoi
    • , Ruxandra Irina Negoi
    • , Josephine W. Ngunjiri
    • , Cuong Tat Nguyen
    • , Long Hoang Nguyen
    • , Dina Nur Anggraini Ningrum
    • , Jean Jacques Noubiap
    • , Malihe Nourollahpour Shiadeh
    • , Peter S. Nyasulu
    • , Felix Akpojene Ogbo
    • , Andrew T. Olagunju
    • , Bolajoko Olubukunola Olusanya
    • , Jacob Olusegun Olusanya
    • , Obinna E. Onwujekwe
    • , Doris D. V. Ortega-Altamirano
    • , Eduardo Ortiz-Panozo
    • , Simon Øverland
    • , Mahesh P. A.
    • , Adrian Pana
    • , Songhomitra Panda-Jonas
    • , Sanghamitra Pati
    • , George C. Patton
    • , Norberto Perico
    • , David M. Pigott
    • , Meghdad Pirsaheb
    • , Maarten J. Postma
    • , Akram Pourshams
    • , Swayam Prakash
    • , Parul Puri
    • , Mostafa Qorbani
    • , Amir Radfar
    • , Fakher Rahim
    • , Vafa Rahimi-Movaghar
    • , Mohammad Hifz Ur Rahman
    • , Fatemeh Rajati
    • , Chhabi Lal Ranabhat
    • , David Laith Rawaf
    • , Salman Rawaf
    • , Robert C. Reiner Jr
    • , Giuseppe Remuzzi
    • , Andre M. N. Renzaho
    • , Satar Rezaei
    • , Aziz Rezapour
    • , Carlos Rios-González
    • , Leonardo Roever
    • , Luca Ronfani
    • , Gholamreza Roshandel
    • , Ali Rostami
    • , Enrico Rubagotti
    • , Nafis Sadat
    • , Ehsan Sadeghi
    • , Yahya Safari
    • , Rajesh Sagar
    • , Nasir Salam
    • , Payman Salamati
    • , Yahya Salimi
    • , Hamideh Salimzadeh
    • , Abdallah M. Samy
    • , Juan Sanabria
    • , Milena M. Santric Milicevic
    • , Benn Sartorius
    • , Brijesh Sathian
    • , Arundhati R. Sawant
    • , Lauren E. Schaeffer
    • , Megan F. Schipp
    • , David C. Schwebel
    • , Anbissa Muleta Senbeta
    • , Sadaf G. Sepanlou
    • , Masood Ali Shaikh
    • , Mehran Shams-Beyranvand
    • , Morteza Shamsizadeh
    • , Kiomars Sharafi
    • , Rajesh Sharma
    • , Jun She
    • , Aziz Sheikh
    • , Mika Shigematsu
    • , Soraya Siabani
    • , Dayane Gabriele Alves Silveira
    • , Jasvinder A. Singh
    • , Dhirendra Narain Sinha
    • , Vegard Skirbekk
    • , Amber Sligar
    • , Badr Hasan Sobaih
    • , Moslem Soofi
    • , Joan B. Soriano
    • , Ireneous N. Soyiri
    • , Chandrashekhar T. Sreeramareddy
    • , Agus Sudaryanto
    • , Mu’awiyyah Babale Sufiyan
    • , Ipsita Sutradhar
    • , PN Sylaja
    • , Rafael Tabarés-Seisdedos
    • , Birkneh Tilahun Tadesse
    • , Mohamad-Hani Temsah
    • , Abdullah Sulieman Terkawi
    • , Belay Tessema
    • , Zemenu Tadesse Tessema
    • , Kavumpurathu Raman Thankappan
    • , Roman Topor-Madry
    • , Marcos Roberto Tovani-Palone
    • , Bach Xuan Tran
    • , Lorainne Tudor Car
    • , Irfan Ullah
    • , Olalekan A. Uthman
    • , Pascual R. Valdez
    • , Yousef Veisani
    • , Francesco S. Violante
    • , Vasily Vlassov
    • , Sebastian Vollmer
    • , Giang Thu Vu
    • , Yasir Waheed
    • , Yuan-Pang Wang
    • , John C. Wilkinson
    • , Andrea Sylvia Winkler
    • , Charles D. A. Wolfe
    • , Tomohide Yamada
    • , Alex Yeshaneh
    • , Paul Yip
    • , Engida Yisma
    • , Naohiro Yonemoto
    • , Mustafa Z. Younis
    • , Mahmoud Yousefifard
    • , Chuanhua Yu
    • , Sojib Bin Zaman
    • , Jianrong Zhang
    • , Yunquan Zhang
    • , Sanjay Zodpey
    • , Emmanuela Gakidou
    •  & Simon I. Hay
  • Article |

    During foraging for live prey, zebrafish larvae alternate between persistent exploitation and exploration behavioural states that correlate with distinct patterns of neuronal activation.

    • João C. Marques
    • , Meng Li
    • , Diane Schaak
    • , Drew N. Robson
    •  & Jennifer M. Li
  • Article |

    The jumbo phage ΦKZ constructs a proteinaceous nucleus-like compartment around its genome that protects phage DNA from degradation by DNA-targeting immune effectors of the host, including CRISPR–Cas and restriction enzymes.

    • Senén D. Mendoza
    • , Eliza S. Nieweglowska
    • , Sutharsan Govindarajan
    • , Lina M. Leon
    • , Joel D. Berry
    • , Anika Tiwari
    • , Vorrapon Chaikeeratisak
    • , Joe Pogliano
    • , David A. Agard
    •  & Joseph Bondy-Denomy
  • Article |

    IL-17a induced by immune activation affects cortical neural activity and promotes social interaction in a mouse model of neurodevelopmental disorders.

    • Michael Douglas Reed
    • , Yeong Shin Yim
    • , Ralf D. Wimmer
    • , Hyunju Kim
    • , Changhyeon Ryu
    • , Gwyneth Margaret Welch
    • , Matias Andina
    • , Hunter Oren King
    • , Ari Waisman
    • , Michael M. Halassa
    • , Jun R. Huh
    •  & Gloria B. Choi
  • Article |

    Whole-exome sequencing of colon organoids derived from patients with ulcerative colitis identifies somatic mutations in components of the IL-17 signalling pathway, which may confer a growth advantage to cells under inflammatory conditions.

    • Kosaku Nanki
    • , Masayuki Fujii
    • , Mariko Shimokawa
    • , Mami Matano
    • , Shingo Nishikori
    • , Shoichi Date
    • , Ai Takano
    • , Kohta Toshimitsu
    • , Yuki Ohta
    • , Sirirat Takahashi
    • , Shinya Sugimoto
    • , Kazuhiro Ishimaru
    • , Kenta Kawasaki
    • , Yoko Nagai
    • , Ryota Ishii
    • , Kosuke Yoshida
    • , Nobuo Sasaki
    • , Toshifumi Hibi
    • , Soichiro Ishihara
    • , Takanori Kanai
    •  & Toshiro Sato
  • Article |

    In patients with ulcerative colitis, chronic inflammation can lead to remodelling of the colorectal epithelium through positive selection of clones with mutations in genes related to IL-17 signalling, which, however, might be negatively selected during colitis-associated carcinogenesis.

    • Nobuyuki Kakiuchi
    • , Kenichi Yoshida
    • , Motoi Uchino
    • , Takako Kihara
    • , Kotaro Akaki
    • , Yoshikage Inoue
    • , Kenji Kawada
    • , Satoshi Nagayama
    • , Akira Yokoyama
    • , Shuji Yamamoto
    • , Minoru Matsuura
    • , Takahiro Horimatsu
    • , Tomonori Hirano
    • , Norihiro Goto
    • , Yasuhide Takeuchi
    • , Yotaro Ochi
    • , Yusuke Shiozawa
    • , Yasunori Kogure
    • , Yosaku Watatani
    • , Yoichi Fujii
    • , Soo Ki Kim
    • , Ayana Kon
    • , Keisuke Kataoka
    • , Tetsuichi Yoshizato
    • , Masahiro M. Nakagawa
    • , Akinori Yoda
    • , Yasuhito Nanya
    • , Hideki Makishima
    • , Yuichi Shiraishi
    • , Kenichi Chiba
    • , Hiroko Tanaka
    • , Masashi Sanada
    • , Eiji Sugihara
    • , Taka-aki Sato
    • , Takashi Maruyama
    • , Hiroyuki Miyoshi
    • , Makoto Mark Taketo
    • , Jun Oishi
    • , Ryosaku Inagaki
    • , Yutaka Ueda
    • , Shinya Okamoto
    • , Hideaki Okajima
    • , Yoshiharu Sakai
    • , Takaki Sakurai
    • , Hironori Haga
    • , Seiichi Hirota
    • , Hiroki Ikeuchi
    • , Hiroshi Nakase
    • , Hiroyuki Marusawa
    • , Tsutomu Chiba
    • , Osamu Takeuchi
    • , Satoru Miyano
    • , Hiroshi Seno
    •  & Seishi Ogawa
  • Article |

    The MYST acetyltransferase HBO1 is a critical regulator in maintaining leukaemia stem cells, and a small-molecule inhibitor of HBO1 is developed that shows efficacy against a range of acute myeloid leukaemia cells.

    • Laura MacPherson
    • , Juliana Anokye
    • , Miriam M. Yeung
    • , Enid Y. N. Lam
    • , Yih-Chih Chan
    • , Chen-Fang Weng
    • , Paul Yeh
    • , Kathy Knezevic
    • , Miriam S. Butler
    • , Annabelle Hoegl
    • , Kah-Lok Chan
    • , Marian L. Burr
    • , Linden J. Gearing
    • , Tracy Willson
    • , Joy Liu
    • , Jarny Choi
    • , Yuqing Yang
    • , Rebecca A. Bilardi
    • , Hendrik Falk
    • , Nghi Nguyen
    • , Paul A. Stupple
    • , Thomas S. Peat
    • , Ming Zhang
    • , Melanie de Silva
    • , Catalina Carrasco-Pozo
    • , Vicky M. Avery
    • , Poh Sim Khoo
    • , Olan Dolezal
    • , Matthew L. Dennis
    • , Stewart Nuttall
    • , Regina Surjadi
    • , Janet Newman
    • , Bin Ren
    • , David J. Leaver
    • , Yuxin Sun
    • , Jonathan B. Baell
    • , Oliver Dovey
    • , George S. Vassiliou
    • , Florian Grebien
    • , Sarah-Jane Dawson
    • , Ian P. Street
    • , Brendon J. Monahan
    • , Christopher J. Burns
    • , Chunaram Choudhary
    • , Marnie E. Blewitt
    • , Anne K. Voss
    • , Tim Thomas
    •  & Mark A. Dawson
  • Article |

    Cryo-electron microscopy structures of the TniQ–Cascade complex encoded by the Vibrio cholerae Tn6677 transposon reveal the mechanistic basis of the functional association of CRISPR- and transposon-associated machineries.

    • Tyler S. Halpin-Healy
    • , Sanne E. Klompe
    • , Samuel H. Sternberg
    •  & Israel S. Fernández
  • Article |

    A cryo-electron microscopy reconstruction shows the ring-shaped structure of the polymerase and capping domains of the L protein bound to a tetramer of phosphoprotein P of the human metapneumovirus.

    • Junhua Pan
    • , Xinlei Qian
    • , Simon Lattmann
    • , Abbas El Sahili
    • , Tiong Han Yeo
    • , Huan Jia
    • , Tessa Cressey
    • , Barbara Ludeke
    • , Sarah Noton
    • , Marian Kalocsay
    • , Rachel Fearns
    •  & Julien Lescar

Amendments & Corrections

  • Author Correction |

    • Philip Jonsson
    • , Chaitanya Bandlamudi
    • , Michael L. Cheng
    • , Preethi Srinivasan
    • , Shweta S. Chavan
    • , Noah D. Friedman
    • , Ezra Y. Rosen
    • , Allison L. Richards
    • , Nancy Bouvier
    • , S. Duygu Selcuklu
    • , Craig M. Bielski
    • , Wassim Abida
    • , Diana Mandelker
    • , Ozge Birsoy
    • , Liying Zhang
    • , Ahmet Zehir
    • , Mark T. A. Donoghue
    • , José Baselga
    • , Kenneth Offit
    • , Howard I. Scher
    • , Eileen M. O’Reilly
    • , Zsofia K. Stadler
    • , Nikolaus Schultz
    • , Nicholas D. Socci
    • , Agnes Viale
    • , Marc Ladanyi
    • , Mark E. Robson
    • , David M. Hyman
    • , Michael F. Berger
    • , David B. Solit
    •  & Barry S. Taylor
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