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Volume 423 Issue 6940, 5 June 2003

Editorial

  • It is ironic, constitutionally questionable and misguided that in pursuit of vaccines against biowarfare agents, the Bush administration has attacked the very biomedical research budgets that have helped to make such defence possible.

    Editorial

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News

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News in Brief

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News Feature

  • Parasites exact a devastating toll on health, particularly in the tropics. Could vaccines based on the sugars on parasite surfaces provide a way to fight back? Carina Dennis investigates.

    • Carina Dennis
    News Feature
  • A bacterium that causes ulcers and stomach cancer is on the decline, but not everyone is celebrating. John Whitfield talks to the experts who have misgivings about its impending extinction.

    • John Whitfield
    News Feature
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Correspondence

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Books & Arts

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Lifeline

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News & Views

  • Two groups, using different approaches, have provided the first quantitative evidence that neurotransmitter release in the brain often occurs by a long-sought 'kiss-and-run' process.

    • Silvio O. Rizzoli
    • William J. Betz
    News & Views
  • The ocean chemistry of 1.5 billion years ago, inferred from rocks of that age, supports the view that marine conditions then were very different from those that pertained at earlier and later times.

    • Matthew T. Hurtgen
    News & Views
  • Starving cancers of oxygen would seem to be a good way of killing them, but the presence of oxygen-deprived areas in tumours appears to correlate with poor prognosis. A molecular explanation for this has now been found.

    • Donald P. Bottaro
    • Lance A. Liotta
    News & Views
  • Hydrogen ions, both positive and negative, have a pervasive influence on the properties of materials and solutions. A unified picture of the behaviour of these ions has now been drawn.

    • Richard M. Martin
    • Giulia Galli
    News & Views
  • The cellular signalling pathway that leads to activation of the NF-κB protein has been studied for many years, and one might think that there's little left to learn. But it still has some surprises in store.

    • Alain Israël
    News & Views
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News and Views Feature

  • Why is the prevalence of type 2 diabetes mellitus now exploding in most populations, but not in Europeans? The genetic and evolutionary consequences of geographical differences in food history may provide the answer.

    • Jared Diamond
    News and Views Feature
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Brief Communication

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Article

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Letter

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Prospects

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Special Report

  • For scientists who want a career in law, the options are greater than ever — and some don't even involve going back to school, says Amy Wilson.

    • Amy Wilson
    Special Report
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