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A checklist of criteria to determine the readiness of high-throughput
‘omics’-based tests for guiding patient therapy in clinical trials is discussed; the
checklist, developed by the US National Cancer Institute in collaboration with
additional scientists with relevant expertise, provides a framework to evaluate the
strength of evidence for a test and outlines practical issues to consider before
using the test in a clinical setting, with an aim to avoid premature advancement of
omics-based tests in clinical trials.
The effects of climate extremes such as droughts or storms on the carbon cycle of ecosystems are investigated; such extremes can decrease regional carbon stocks.
Fabrication techniques developed for graphene research allow the disassembly of many layered crystals (so-called van der Waals materials) into individual atomic planes and their reassembly into designer heterostructures, which reveal new properties and phenomena.
Strongly connected and interdependent networks create risks of global-scale catastrophic failure; to make networked risks more manageable, it is suggested to establish a ‘Global Systems Science’.
This Perspective discusses the emerging advances in plant membrane transporters, which can be used to improve crop yields, nutritional value, and environmental stress resistance.
