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This paper presents an analytical theory of the dynamical evolution of ecosystems, which is in good accord with the species turnover distribution in the tropical forest of Barro Colorado Island in Panama.
Lead isotope records from rocks from the floor of the North Atlantic Ocean, combined with a simple quantitative model, are used to reconstruct chemical weathering rates in glaciated regions of North America over the past 550,000 years. This shows that chemical weathering rates in these regions were two to three times lower than today during glacial periods.
An inhibitor of SecinH3 is identified, and shows that treatment of mice with this molecule induces hepatic insulin resistance, an early step in the development of type 2 diabetes.
A spin-polarized 'ferromagnetic' superfluid phase in 3He is thought to arise when a condensate of paired nuclear spins aligns itself along the direction of an applied magnetic field.
A mechanical spin density detector is developed that enables measurements of the spin behaviour in this phase to be performed as the temperature, pressure and magnetic field are varied
A major carbohydrate transporter, GpMST1, is characterized by exploiting the symbiosis between Geosiphon pyriformis and the cyanobacterium Nostoc punctiforme.
A complementary study to that of Famulock et al. shows that feeding SecinH3 to flies inhibits steppke, a cytohesin, leading to growth defects and a block in insulin signalling.
This paper, one of two published that show Sld2 and Sld3 constitute the minimal group of cyclin-dependent kinase (CDK) targets necessary to promote replication, also finds that the function of G1 CDKs in replication is not just to activate the S-phase CDKs, but also to regulate the Cdc7 kinase regulatory subunit, Dbf4.
One of two papers that describe how botulinum toxins produced by Clostridium botulinum are potent inhibitors of neurotransmitter release by elucidating the crystal structure of botulinum toxin B bound to its receptor.
One of two papers that describe how botulinum toxins produced by Clostridium botulinum are potent inhibitors of neurotransmitter release by elucidating the crystal structure of botulinum toxin B bound to its receptor.
Identification of two CO2 receptors in Drosophila antennae, Gr21a and Gr63a, determines that their co-expression is necessary and sufficient for CO2 sensing. Flies lacking one of the two are insensitive to CO2, and confer CO2 responsivity when both receptors are expressed in heterologous neurons.
The heat-shock protein Hsp70 can regulate the development of red blood cells, or erythropoiesis. Hsp70 interacts with GATA-1 and protects it from cleavage, thus controlling the differentiation of erythrocytes by its presence in the nucleus.