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RNA-dependent RNA synthesis in rat brain

Abstract

RIBONUCLEIC acid-dependent RNA polymerase (replicase) was first isolated from Escherichia coli infected with RNA bacteriophage Q β which has specific template requirements1. Such an enzyme has been described in tumour cells and several types of mammalian cells infected with RNA viruses2–5.

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MIKOSHIBA, K., TSUKADA, Y., HARUNA, I. et al. RNA-dependent RNA synthesis in rat brain. Nature 249, 445–448 (1974). https://doi.org/10.1038/249445a0

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