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Hydrogen Ion and the Activation of Electrically Excitable Membranes

Abstract

Some experimental results can be interpreted as an indication that permeability changes of nerve membranes are mediated by migration of hydrogen ions.

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References

  1. Waddell, W. J., and Bates, R. G., Physiol. Rev., 49, 285 (1969).

    Article  CAS  Google Scholar 

  2. Waddell, W. J., and Butler, T. C., J. Clin. Invest., 38, 720 (1959).

    Article  CAS  Google Scholar 

  3. Caldwell, P. C., J. Physiol., 142, 22 (1958).

    Article  CAS  Google Scholar 

  4. Spyropoulos, C. S., J. Neurochem., 5, 185 (1960).

    Article  CAS  Google Scholar 

  5. Carter, N. W., Clin. Res., 9, 177 (1961).

    Google Scholar 

  6. Carter, N. W., Rector, F. C., Campion, D. S., and Seldin, D. W., J. Clin. Invest., 46, 920 (1967).

    Article  CAS  Google Scholar 

  7. Chandler, W. K., and Meves, H., J. Physiol., 180, 788 (1965).

    Article  CAS  Google Scholar 

  8. Frankenhauser, B., and Hodgkin, A. L., J. Physiol., 137, 218 (1957).

    Article  Google Scholar 

  9. Hodgkin, A. L., and Huxley, A. F., J. Physiol., 116, 497 (1952).

    Article  CAS  Google Scholar 

  10. Hodgkin, A. L., and Keynes, R. D., J. Physiol., 138, 253 (1957).

    Article  CAS  Google Scholar 

  11. Moore, J. W., and Narahashi, T., Fed. Proc., 26, 1655 (1967).

    CAS  PubMed  Google Scholar 

  12. Cole, K. S., and Moore, J. W., Biophys. J., 1, 1 (1960).

    Article  ADS  CAS  Google Scholar 

  13. Stephens, W. G. S., and Steven, F. S., J. Phys. Chem., 67, 2843 (1963).

    Article  CAS  Google Scholar 

  14. Keynes, R. D., Proc. Roy. Soc., B, 142, 359 (1954).

    ADS  CAS  Google Scholar 

  15. Keynes, R. D., J. Physiol., 169, 690 (1963).

    Article  CAS  Google Scholar 

  16. Caldwell, P. C., and Keynes, R. D., J. Physiol., 154, 177 (1960).

    Article  CAS  Google Scholar 

  17. Hodgkin, A. L., and Huxley, A. F., J. Physiol., 117, 500 (1962).

    Article  Google Scholar 

  18. Hodgkin, A. L., and Katz, B., J. Physiol., 108, 37 (1949).

    Article  CAS  Google Scholar 

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STEPHENS, W. Hydrogen Ion and the Activation of Electrically Excitable Membranes. Nature 224, 547–549 (1969). https://doi.org/10.1038/224547a0

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