Abstract
THE importance of reactions in which electron transport from reduced pyridine nucleotides to oxygen is coupled with the formation of adenosine triphosphate from adenosine diphosphate and inorganic phosphate is well recognized by biochemists. Although much pertinent information has been accumulated, no clear picture of the sites and mechanism of uptake of inorganic phosphate coupled with electron transport has yet been obtained. This communication gives some results of exchange reactions of inorganic phosphate labelled with phosphorus-32 and oxygen-18 which may give some additional insight concerning oxidative phosphorylation, together with a brief presentation of a hypothesis for the mechanism of coupling of electron transport with inorganic phosphate uptake.
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BOYER, P., FALCONE, A. & HARRISON, W. Reversal and Mechanism of Oxidative Phosphorylation. Nature 174, 401–402 (1954). https://doi.org/10.1038/174401b0
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DOI: https://doi.org/10.1038/174401b0
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