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  • Special |

    At 0:59 GMT on 26 12 2004, the India tectonic plate slid underneath its neighbour, raising it by about 10 metres. The earthquake caused a powerful tsunami that devastated coastlines around the Indian Ocean.

  • Collection |

    In 1905, Albert Einstein submitted five papers for publication in Annalen der Physik, covering three topics: the photoelectric effect, brownian motion, and the special theory of relativity. Although diverse in subject matter, these contributions are landmarks in their field - and testament to Einstein's genius. To honour their centenary, 2005 has been designated 'World Year of Physics'.Naturejoins the celebrations with the publication of this special supplement.

  • Special |

    In 1905, Albert Einstein submitted five papers for publication in Annalen der Physik, covering three topics: the photoelectric effect, Brownian motion, and the special theory of relativity.

  • Special |

    Titan, Saturn's largest moon, truly deserves its name. Larger than the planet Mercury, it has a dense atmosphere filled with photochemical smog that shrouds the moon's surface in mystery. What lies beneath? The only way to be sure is to send a probe through the clouds. The Cassini craft has taken seven years to carry the Huygens probe to Titan. Naturewatches as its moment in the spotlight draws near.

  • Special |

    Biology is overwhelmed with data. Here, Nature's focus on Computational Biology provides a diverse set of reviews giving an overview of the areas of molecular cell biology that are embracing the application of mathematical theory to advance discovery.

  • Special |

    Dolly, the world's first animal to be cloned from an adult cell, died in February 2003. Here, Naturereflects on the life of this extraordinary sheep.

  • Special |

    Naturepresents a collection of articles and graphics that celebrate the historical, scientific and cultural impacts of the discovery of the double helix.

  • Special |

    Natureis proud to present the complete initial sequence and analysis of the mouse genome - the experimental key to the human genome.

  • Special |

    This year saw a huge range of discoveries in the world of science, as well as the launch of Nature news.

  • Insight |

    "Space", as Douglas Adams famously said, "is big. You just won't believe how vastly, hugely, mind-bogglingly big it is." Change 'space' to 'chemical space', and his statement has similar resonance: the total number of possible small organic molecules that populate 'chemical space' has been estimated to exceed 1060 - an amount so vast when compared to the number of such molecules we have made, or indeed could ever hope to make, that it might as well be infinite. So, it is not surprising that our exploration of chemical space has so far been extremely limited.

  • Insight |

    The development of cancer can be viewed as an evolutionary process. Cells are constantly subject to mutations in their DNA which are usually detrimental to the cell. But occasionally these changes produce cells that can escape the normal constraints and flourish as pathological tumours.

  • Special |

    Technological innovations in detecting and studying protein-protein interactions are providing new ways of doing research in cell signalling. Diane Gershon investigates.