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Human genetic evidence increases the success rate of drugs from clinical development to approval but we are still far from reaching peak genetic insights to aid the discovery of targets for more effective drugs.
Efficiency roll-off in a wide range of TADF OLEDs is analysed and a figure of merit proposed for materials design to improve efficiency at high brightness, potentially expanding the range of applications of TADF materials.
A study examining how cities can foster well-being and positive mental health in young residents synthesizes opinions from researchers, practitioners, advocates and young people, highlighting factors that policymakers and urban planners should consider.
Analyses of drivers of water stress are used to predict likely trajectories of the Amazon forest system and suggests potential actions that could prevent system collapse.
