News & Views in 2003

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  • It has long been proposed that stem cells function by dividing to generate an identical daughter cell and a cell that becomes more specialized. New work illustrates such asymmetric division and its molecular basis.

    • Haifan Lin
    News & Views
  • Lack of oxygen causes the cells of certain tumours to spread to new locations. It also activates a homing mechanism that enables the migrating cells to target specific organs.

    • René Bernards
    News & Views
  • Pairs of viral genomes work together to destroy their hosts more quickly. How this might occur remains unknown, but study of the phenomenon should provide insight into how genetic systems evolve.

    • Steven A. Frank
    News & Views
  • Sifting of organic residues from ancient rocks has netted a catch of tiny fossils that provide clues about when plant life first appeared on land.

    • Paul Kenrick
    News & Views
  • Information about atmospheric conditions far back in Earth's history is embedded in the isotopic composition of fossil microbes. Such studies are technically demanding, but hold considerable promise.

    • Stephen J. Mojzsis
    News & Views
  • A centuries-old technique for transporting timber is the inspiration for a new method of assembling nanowires into large-scale, ordered patterns that could form the basis of a new generation of electronic devices.

    • Peidong Yang
    News & Views
  • A form of gene regulation that uses small RNA molecules to bind to longer RNAs was first described over a decade ago, but was thought to be of little significance in controlling cellular processes. No longer.

    • Philip N. Benfey
    News & Views
  • A laser that operates through repeated emission from a single atom is very different from the lasers we know. The beam of light produced has a more orderly photon stream than even the quietest laser.

    • Howard Carmichael
    • Luis A. Orozco
    News & Views
  • Random collisions between asteroids would seem to cause their spin axes to be tilted in all directions. Surprisingly, the gentle recoil force of thermal re-radiation may bring their spin axes into alignment.

    • Richard P. Binzel
    News & Views
  • The mechanism by which the TIMP-2 protein inhibits blood-vessel formation has been uncovered — and it is not as expected. The finding has implications for treating a cancer by cutting off its blood supply.

    • Edward M. Conway
    • Peter Carmeliet
    News & Views
  • Reducing food intake increases lifespan in many species. A small molecule that occurs naturally in plants seems to mimic the beneficial effects of caloric restriction and extend longevity in yeast.

    • Toren Finkel
    News & Views