Review, News & Views, Perspectives, Hypotheses and Analyses in 2006

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  • Before hydrogen can be used as a transportation fuel, a safe storage system for the gas must be found. Metal clusters that release hydrogen in response to an electric current may be a step in the right direction.

    • Masanori Takimoto
    • Zhaomin Hou
    News & Views
  • Big conclusions can be drawn from the tiny ecosystems that flourish in carnivorous pitcher plants. Manipulating habitat size and predator abundance reveals which is more important to ecosystem dynamics.

    • Jonathan B Shurin
    News & Views
  • Genetic dissection of a yeast gene-regulatory pathway shows that the logical output of such a pathway can remain the same even though the molecular mechanisms underlying the output have diverged remarkably.

    • Antonis Rokas
    News & Views
  • The proliferation of cells must balance the longevity assured by tissue renewal against the risk of developing cancer. The tumour-suppressor protein p16INK4a seems to act at the pivot of this delicate equilibrium.

    • Christian M Beausejour
    • Judith Campisi
    News & Views
  • Bose–Einstein condensation occurs when many particles enter into the same, coherent quantum state, and is now claimed to occur in various systems of 'quasiparticles' in solids. But is it the right term to use here?

    • David Snoke
    News & Views
  • Satellite measurements of changes in Earth's gravity field reveal ice loss from Greenland's ice sheet. Over the past four years, this melt has contributed to global sea-level rise at an accelerating rate.

    • Tavi Murray
    News & Views
  • How does one best search for non-replenishable targets at unknown positions? An optimized search strategy could be applied to situations as diverse as animal foraging and time-sensitive rescue missions.

    • Michael F. Shlesinger
    News & Views
  • The three-million-year old skeleton of a three-year-old child provides an outstanding resource to understand the development of a human ancestor that seems to have both walked upright and climbed through trees.

    • Bernard Wood
    News & Views
  • HIV-1 prompts a massive cellular immune response, but eventually it tires the immune cells. Blocking the activation of a cell receptor called PD-1 might restore these exhausted cells.

    • Sarah Rowland-Jones
    • Tao Dong
    News & Views
  • Thermonuclear supernovae were thought to occur only when white-dwarf stars of a certain mass explode. The discovery of a supernova that is way over the mass limit might require a reworking of the model.

    • David Branch
    News & Views
  • Embryonic stem cells are prized for their ability to mature into all the specialized adult cell types. It may now be possible to reprogramme adult body cells to have the characteristics of stem cells.

    • M. Azim Surani
    • Anne McLaren
    News & Views
  • Many drugs isolated from microorganisms have complex molecular structures, making it difficult for chemists to modify them. But it seems that enzymes can provide a short cut to drug variants.

    • Christopher T. Walsh
    News & Views
  • Gutless marine worms harness the resources of a team of bacteria in lieu of a digestive or excretory system. A genome-sequence analysis now defines the roles of the microbes.

    • David A. Stahl
    • Seana K. Davidson
    News & Views
  • Oxygen crystallizes into a sequence of structures, starting as an insulator at low pressure and becoming a superconductor at high pressure. The elusive structure of an intermediate phase has now been determined.

    • Burkhard Militzer
    • Russell J. Hemley
    News & Views
  • The latest surveys provide evidence for one, maybe two, galaxies farther back in cosmic time than ever detected before. But does the fact that we don't see more mean these are the very first galaxies to be formed?

    • Richard McMahon
    News & Views
  • Multidrug transporters provide cells with a defence against toxic chemicals, but they are also responsible for drug resistance. The structures of two such transporters reveal novel aspects of their mechanisms.

    • Shimon Schuldiner
    News & Views