News & Views in 2004

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  • The diversity of cellular stresses that activate the 'guardian of the genome' — p53 — begs the question of how these signals all converge on one protein. Perhaps the key to this integration is the nucleolus.

    • Henning F. Horn
    • Karen H. Vousden
    News & Views
  • Global warming is altering the distribution and abundance of plant and animal species. Application of a basic law of ecology predicts that many will vanish if temperatures continue to rise.

    • J. Alan Pounds
    • Robert Puschendorf
    News & Views
  • Computer simulations and laboratory experiments have shed light on how an asymmetric pattern of gene expression is fixed in vertebrate embryos — an early step towards asymmetric development of the internal organs.

    • Nick Monk
    News & Views
  • A supernova seen in 1993 defied explanation. Astronomers suspected the dying star had lost much of its hydrogen before the explosion. The discovery of a companion to this star suggests where that gas went...

    • Thomas Matheson
    News & Views
  • Microscopic glass beads coated with lipid membranes provide a sensitive detector of interactions between proteins and ligands. The changing spatial order of the array of beads in solution is the key.

    • Thomas M. Bayerl
    News & Views
  • A fossil skull from China, dating to 55 million years ago, provides much-needed substantial evidence of early primates in Asia. Interpretation of the creature's eye size and activity pattern will spark debate.

    • Robert D. Martin
    News & Views
  • On Earth, no living organism can function without water. It is, in the words of Albert Szent-Györgyi, the matrix of life. But is it reasonable to assume that this maxim holds on other worlds too?

    • Philip Ball
    News & Views
  • Physical processes in the Southern Ocean largely control nutrient distribution in the global marine environment, a finding that further highlights the influence of this oceanic region on Earth's climate.

    • Joachim Ribbe
    News & Views
  • Newly made proteins are moved across cellular membranes through a protein channel. The crystal structure of this channel is now revealed and confirms expectations that it must change shape to allow proteins to pass.

    • Jordi Benach
    • John F. Hunt
    News & Views
  • Neurons in the retina turn on and off rapidly in response to light. With the discovery of mutations in human genes that mediate this quick turn-off, we have the first picture of its importance in visual perception.

    • Kendall J. Blumer
    News & Views
  • The manipulation of electronic spins — 'spintronics' — might be the basis of future device technology. A subtle relativistic effect offers a way to flip spins inside a semiconducting material.

    • Michael E. Flatté
    News & Views