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Efforts to discourage new smokers and help people to quit are bringing smoking rates down in many places, but it’s going to take more to put an end to tobacco smoking altogether.
The chemical composition of the Galactic halo star J1010+2358 shows extremely low sodium and cobalt abundances, different from most other halo stars, indicative of a very metal-poor star being seeded with elements from a pair-instability supernova.
Our experimental proof of chiral phonons demonstrates a degree of freedom in condensed matter that is of fundamental importance and opens the door to exploration of emergent phenomena based on chiral bosons.
Genome sequencing of nine individuals shows ancestry shifts in the Neolithization of northwestern Africa that probably mirrored a heterogeneous economic and cultural landscape in a more multifaceted process than observed in other regions.
Covalent organic molecules can be combined with ionic inorganic molecules to create a hybrid material demonstrating paradoxical mechanical properties in a bottom-up manner, enabling the manufacture of an ‘elastic ceramic plastic’.
A new intracellular agonist-binding pocket is identified that is common to many G protein-coupled receptors, which will have implications for the development of biased compounds that target this large group of receptors.
Micronuclei, which are common features of nuclei in cancer cells, can generate heritable sources of transcriptional suppression, a finding that establishes an inherent relationship between chromosomal instability and variation in chromatin state and gene expression.
Analysis of new geologic and palaeoseismic data using a 3D finite-element model suggests that the past six major earthquakes on the southern San Andreas Fault were probably triggered by highstands of ancient Lake Cahuilla.
Analysis of dendrite initiation, owing to filling of pores with lithium by means of microcracks, and propagation, caused by wedge opening, shows that there are two separate processes during dendrite failure of lithium metal solid-state batteries.
Missegregated chromosomes that are sequestrated in micronuclei are subject to changes in histone modifications leading to abnormalities in chromatin accessibility that remain long after the chromosomes have been reincorporated into the primary nucleus.
Artificial intelligence goes beyond the current state of the art by discovering unknown, faster sorting algorithms as a single-player game using a deep reinforcement learning agent. These algorithms are now used in the standard C++ sort library.
This study reveals how Klotho and heparan sulfate glycosaminoglycan coreceptors enable FGF hormones to induce asymmetric 1:2 FGF–FGFR dimerization mandatory for FGFR kinase activation and hence signalling.
A structural and functional analysis of the systems involved in oligosaccharide uptake in gut Bacteroidetes describes multicomponent complexes termed utilisomes that include pre-processing and transport subunits.
