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Iron atoms in a synthetic metal–sulfur cluster can capture nitrogen and catalyse its silylation, demonstrating successful nitrogen reduction by iron atoms in a sulfur-rich environment.
Experiments in mice show that direct- and indirect-pathway neurons in the basal ganglia are co-activated during movement but exhibit opposite patterns of activity during the active suppression of movement.
This study provides a comprehensive spatiotemporal map of human and mouse gonadal differentiation, using a combination of single-cell and spatial transcriptomics, chromatin accessibility assays and fluorescent microscopy, which can guide in vitro gonadogenesis.
Active super-enhancers are highly and specifically hypermutated in 92% of diffuse large B cell lymphoma samples and display signatures of activation-induced cytidine deaminase activity, leading to the dysregulation of genes encoding B cell developmental regulators and oncogenes.
Using differences among strains as a model for inter-individual variation, this paper identifies a conserved metabolicadaptation in C. elegans that compensates for genetic variation.
High-resolution volumetric calcium imaging was used to create a functional atlas of the Drosophila melanogaster ventral brain and identify how and where metabolic and reproductive states alter processing of food-related sensory stimuli.
Immune tolerance to food is mediated by CD4+ T cells forming subsets of T helper cells lacking the capacity to trigger gut pathology but able to produce regulatory T cells that may suppress it.
The molecular mechanism by which FERONIA, LORELEI and NORTIA work together to facilitate calcium-mediated synergid–pollen tube communication in flowering plants is presented.
An online training module that synergistically targets two different mindsets can reduce stress levels in adolescents in the context of social-evaluative stressors—stressful experiences in which individuals fear that others are judging them negatively.