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The fate of implanted biomaterials and biomedical devices can be investigated by intravital microscopy in animal models to reveal regenerative and potentially pathological responses to the implant, such as the foreign body response. The cover image shows a three-dimensional reconstruction of a polycaprolactone electrospun scaffold, capturing second-harmonic generation and third-harmonic generation by nonlinear multiphoton microscopy. See Eleonora Dondossola & Peter Friedl.
Image: Eleonora Dondossola. Cover design: Charlotte Gurr
The Materials Research Society (MRS) fall meeting is a fixture in the conference calendar of the global materials science community. This year, for the very first time, the conference went hybrid, posing new opportunities, but also challenges, for organizers, speakers and attendees.
Bioengineered platforms, intended to be used in the investigation of human health and disease, often incorporate cells of unknown ancestry or that lack diversity. To develop tools and platforms that benefit the entire human population, we must consider the ancestry of cells and intentionally diversify the cells we use in our designs.
An article in Nature Nanotechnology reports the transport and interaction mechanisms of short interfering RNA-delivering gold nanoparticles in plant leaves.
The integration and function of implanted biomaterials and devices depend on the responses of the host tissue, such as macrophage activation and neovascularization. This Review discusses how intravital microscopy can be applied to assess the mechanisms underlying regenerative and pathological responses to implants.
Liquid crystalline elastomers are stimuli-responsive polymeric materials whose mechanical properties can be programmed by patterning their local orientation, making them promising candidates to serve as low-density actuators and functional elements in various applications. This Review discusses the synthesis and processing of liquid crystalline elastomers, with a focus on alignment methods and potential applications.
The development of antibiotic tolerance and resistance has demanded the search for alternative antibacterial therapies. This Review discusses antibacterial biomaterials and biomaterial-assisted delivery of non-antibiotic therapeutics for the treatment of bacterial infectious diseases, with a focus on clinical translation.
The CO2 reduction reaction can be used to produce carbon-neutral chemicals using renewable electricity. This Review presents material design strategies for controlling the transport of products and reactants in electrochemical reactors that convert CO2 emissions into chemicals and fuels.