Volume 4 Issue 3, March 2020

Atomistic simulations reveal details on phase transition and lateral organization of domains in model cellular membranes.

Copper efflux oxidase is a special oxygen reduction electrocatalyst with five copper binding sites. Mutations at the fifth site can give highly active variants and tell us which factors are important for catalysis.

Microorganisms enzymatically degrade natural polymers and synthetic plastics to enable a sustainable environment. This Review describes common features of these enzymes and how they can be harnessed to convert waste into useful precursors.

Organic materials can serve as sustainable electrodes in lithium batteries. This Review describes the desirable characteristics of organic electrodes and the corresponding batteries and how we should evaluate them in terms of performance, cost and sustainability.

In this Review, the authors describe single-cell protein analysis technologies and assess their advantages and limitations. The emerging technologies presented have the potential to reveal new insights into tumour heterogeneity and therapeutic resistance, elucidate mechanisms of immune response and immunotherapy, and accelerate drug discovery.

A hollow multishell structure can feature voids between porous shells that allow it to controllably release multiple guests or play host to cascade reactions. This Perspective describes host–guest chemistry and the temporal–spatial ordering and dynamic responses of multishell structures to their environment.