Initial submission

On this page: Brief guide to submission | Cover letter | Initial format requirements | Presubmission enquiries | Submission policies

Brief guide to submission

Please see our brief guidelines for preparing initial submissions, and our brief guide to manuscript submission for an overview of key information on submitting primary research for publication in Nature Biomedical Engineering.

Cover letter

Authors should provide a cover letter that briefly discusses the significance and broad relevance of the work, and explains its scientific context. The cover letter should help the editors determine whether the work is appropriate for Nature Biomedical Engineering. Any prior discussions with an editor of the journal about the work should also be mentioned. The cover letter can also be used to suggest names, affiliations, e-mail address and expertise of potential referees, as well as any request to exclude particular scientists or laboratories as referees.

Initial format requirements

The Nature journals are flexible with regard to the format of initial submissions. Within reason, style and length will not influence consideration of a manuscript. However, to facilitate the editorial and review processes we strongly encourage you to incorporate the manuscript text and figures into a single PDF file with all lines numbered or a Microsoft Word file (the manuscript tracking system will automatically number lines). Please insert suitably high-resolution figures within the text at appropriate positions. Each figure legend should appear on the same page as its figure. The reference list should include article titles.

Although not required at the initial submission stage, authors are encouraged to review the article format requirements for final submission so that they can familiarize themselves with what will be required if the editor invites submission of a revised version of the manuscript.

Presubmission enquiries

Researchers may request feedback from the editors on whether a potential manuscript may be appropriate for the journal. Presubmission enquiries are optional and should not be used to submit a full manuscript. If your manuscript has already been written, please proceed with a full submission.

Submission policies

Submission to Nature Biomedical Engineering is taken to imply that there is no significant overlap between the submitted manuscript and any other papers from the same authors under consideration or in press elsewhere (abstracts or unrefereed preprints do not compromise novelty). The authors must include copies of all related manuscripts with any overlap in authorship that are under consideration or in press elsewhere. If a related manuscript is submitted elsewhere while the manuscript is under consideration at Nature Biomedical Engineering, a copy of the related manuscript should be sent to the editor.

The primary affiliation for each author should be the institution where the majority of their work was done. If an author has subsequently moved, their current address may also be stated.

If the manuscript includes personal communications, please provide a written statement of permission from any person who is quoted. E-mail permission messages are acceptable.

For life sciences manuscripts reporting original research results, please be aware that an editorial policy checklist (to ensure compliance with Nature Research editorial policies) and a completed reporting summary (to promote consistency and transparency in reporting) will be required before the manuscript is sent for external peer review. Some types of research require additional methodological details, which are captured in accessory reporting summaries:

The reporting summary and associated accessory summaries will be made available to reviewers and will be published with all accepted manuscripts. For more information, see reporting life sciences research.

Please note that because of the advanced features used in these forms, you must use Adobe Reader to open the documents and fill them out.

Additional editorial policies can be found on the Nature journals policies page.