Review Articles in 2018

This Review summarizes the medical applications of artificial intelligence, and its economic, legal and social implications for healthcare.

This Review discusses the manufacturing of cell products for clinically advanced cell therapies, and highlights potential manufacturing bottlenecks and solutions towards the cost-effective commercialization of the therapies.

This Review discusses the manipulation and use of human pluripotent stem cells and their progeny for the regeneration of the cardiovascular system.

This Review discusses the main diagnostic and therapeutic applications of synthetic gene circuits, and their translational prospects.

This Review Article provides an overview of chimeric antigen receptors (CARs) for T cells and discusses engineering strategies for the design of next-generation CAR-T therapies for haematologic and solid cancers.

This Review discusses technology for the isolation and phenotypic profiling of circulating tumour cells from blood for the identification of those with high metastatic potential as well as requirements for clinical applications of the cells.