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  • New wrinkles on the Nobel prize-winning method are creating new efficiencies, and new research opportunities.

    • Jim Kling
    Technology Feature
  • Journeying into the field to study a model organism in its natural habitats.

    • Ellen P. Neff
    Technology Feature
  • Studying potentially dangerous microbes in animal models of the disease they cause takes some extra considerations, as researchers and staff must perform their work under the careful restrictions of different biosafety level laboratories.

    • Jim Kling
    Technology Feature
  • Engineers and neuroscientists working to advance multiphoton microscopy are pushing the depths, speeds, and scales of in vivo imaging.

    • Ellen P. Neff
    Technology Feature
  • Researchers are building better barcodes and combining spatial and temporal tools to trace cell lineages from the earliest stages of animal development—and beyond.

    • Jim Kling
    Technology Feature
  • As metagenomics advances, virus hunters are finding novel infections in colonies of laboratory mice across the world. What that means for scientific research and the animals themselves can depend on the mouse.

    • Alla Katsnelson
    Technology Feature
  • As COVID-19 continues to spread, the urgency of the hunt for effective therapeutics and vaccines has likewise grown. As with past outbreaks, animal models will be an important component of efforts to understand how the SARS-CoV-2 virus causes disease, and how best to defeat it.

    • Michael Eisenstein
    Technology Feature
  • To bridge brains and make the most of their nonhuman primate models, neuroscientists are setting standards, building tools, and starting to share their neuroimaging data.

    • Ellen P. Neff
    Technology Feature
  • As researchers look for more mammalian alternatives, an old moth is learning new tricks.

    • Jim Kling
    Technology Feature