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In this review, previous studies have demonstrated that TRT may be associated with decreased rates of adverse cardiovascular events with lower morbidties and mortality. Crucial outcomes of future randomized trials such as the TRAVERSE STUDY—Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men is eagerly awaited to shed some light on the safety and potential impact of TRT use on cardiovascular health and risks. Until then, it is recommended that clinicians carefully monitor potential cardiac side effects of patients using TRT.
