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This image depicts a process where a river overflows its banks. Dikes built on the river play a key role in protecting its surrounding farmland from flooding. Likewise, during the development of solid tumors, malignant tumors continue to grow (surging flooding), constantly erode the invasive zone (dikes along the river) and destroy paratumoral tissues (normal farmland). See page 585–603 by Liang Wu et al. for details.