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  • In this Comment, Naveen Tangudu and Katherine Aird discuss recent findings showing that 53BP1 regulates heterochromatin through liquid-liquid phase separation.

    • Naveen Kumar Tangudu
    • Katherine M. Aird
    Comment Open Access
  • Cunningham et al. comment on the U.K.’s commitment to protect 30% of land by 2030, by identifying priority landscapes for expansion of the current protected area network in the UK using 445 priority species ranges across the country, under two baseline protection definitions to reach this conservation target. They find that expanding the protected area network by initially only including the strictest protected areas would yield much greater representation of threatened species, and propose new considerations for protected area commitments.

    • Charles A. Cunningham
    • Humphrey Q. P. Crick
    • Colin M. Beale
    Comment Open Access
  • Jasmine Miller-Kleinhenz et al. highlight the risk of science and academia’s general neutrality to discussions around race and social justice. Their collectively-developed course represents a framework to begin these important discussions and improve conversations on race in academia.

    • Jasmine M. Miller-Kleinhenz
    • Alexandra B. Kuzmishin Nagy
    • Ida T. Fonkoue
    Comment Open Access
  • García Saura et al. report a new tool, MacroGreen, to detect ADP-ribosylation by GFP fluorescence in a microplate reader, or in cells by microscopy. With superior affinity and reduced ADP-ribosyl hydrolase activity, MacroGreen is an easy to produce and suitable tool for rapid detection of ADP-ribosylated proteins in vitro without a need for specialist reagents and time-consuming methods.

    • Antonio Ginés García-Saura
    • Laura K. Herzog
    • Herwig Schüler
    Comment Open Access
  • In a recent issue of Science Advances, Srivastava et al. report a novel nucleotide biosynthesis regulatory role for UBR7 in NOTCH1-driven T-ALL. Here we will discuss their key findings and the implications for using cancer metabolism to understand the development and progression of T-ALL.

    • Andrew Volk
    Comment Open Access
  • Gillman and Wright propose a re-evaluation of taxonomical nomenclature to reinstate indigenous species names. These authors discuss the consideration of indigenous names for new and existing species in order to reflect the importance and precedence of indigenous knowledge in biology.

    • Len Norman Gillman
    • Shane Donald Wright
    Comment Open Access
  • Adree Khondker and Maikel Rheinstadter discuss how bacteria escape being killed by polymyxin antibiotics. Touching on their recent Communications Biology paper, they elaborate on the mechanism by which the bacterial membrane becomes resistant and on future directions to take in order to understand this phenomenon.

    • Adree Khondker
    • Maikel C. Rheinstädter
    Comment Open Access
  • Research from Helen Goodridge and Clive Svendsen’s groups published in Communications Biology showed that young bone marrow transplantation slows down cognitive decline in old mice. The authors now discuss subsequent studies examining the relationship between blood components and aging-associated cognitive impairment and rejuvenation as well as their own ongoing work.

    • Seokjo Kang
    • V. Alexandra Moser
    • Helen S. Goodridge
    Comment Open Access
  • Yamamoto and Higashido discuss the possible routes of the hormone oxytocin in the body, and highlight their recent study in Communications Biology where they showed that the RAGE receptor is a transporter for oxytocin across the blood−brain barrier.

    • Yasuhiko Yamamoto
    • Haruhiro Higashida
    Comment Open Access
  • Following up on their recent study in Communications Biology Sasha Tetu et al discuss how plastic pollution of the oceans may affect marine microbes as well as strategies to identify the substances responsible for leachate toxicity and to further understand their impact.

    • Sasha G. Tetu
    • Indrani Sarker
    • Lisa R. Moore
    Comment Open Access
  • In light of their recent finding that insertion of a rare endogenous retrovirus, β4, is the cause of the characteristic coat coloring in agouti and piebald mice, Akira Tanave and Tsuyoshi Koide now discuss the origin and expansion of this element as well as potential roles of β4 in the mouse genome.

    • Akira Tanave
    • Tsuyoshi Koide
    Comment Open Access
  • Karen Echeverri and her colleagues showed in their recent Communications Biology study that an unconventional Fos/Jun heterodimer regulates axon regeneration in axolotl. In this article, she emphasises the diverse mechanisms of regeneration in other species and discusses future work needed to understand how the nervous system can be regenerated.

    • Karen Echeverri
    Comment Open Access
  • Genomic diversity is a driving force influencing human and animal health, and susceptibility to disease. During the Keystone Symposium on Leveraging Genomic Diversity to Promote Human and Animal Health held in Kampala on Lake Victoria in Uganda, we brought together diverse communities of geneticists with primary objectives to explore areas of common interest, joint technological and methodological developments and applications, and to leverage opportunities for cross-learning. We explored translational genomics research in farmed animals and humans, debated the differences in research objectives in high- and low-resourced environments, delved into infectious diseases and zoonoses affecting humans and animals and considered diversity and cultural context at many levels. The 109 participants were from 22 countries (13 in Africa) and included 44 global travel awardees from 9 countries, equal numbers of men and women, of whom 31 were students and 13 senior investigators.

    • Michèle Ramsay
    • Han G. Brunner
    • Appolinaire Djikeng
    Comment Open Access
  • Venkatesan and Coskun propose the use of digital posters instead of paper posters for disseminating progress reports in scientific meetings. These digital frames are capable of uploading multiple display items via wireless network and changing the interactive display with wave of a hand over an attached motion sensor.

    • Mythreye Venkatesan
    • Ahmet F. Coskun
    Comment Open Access