Focus |

Organic Chemistry and Chemical Biology

  • Nature Communications | Article | open

    Two photon polymerization (TPP) allows nanofabrication of three dimensional objects with complex geometries, but is considered to be slow with a limited fabrication rate. Here the authors present a TPP technique based on a digital mirror device scanner which allows for fast parallel nanofabrication with improved precision and flexibility.

    • Qiang Geng
    • , Dien Wang
    • , Pengfei Chen
    •  &  Shih-Chi Chen
  • Nature Communications | Article | open

    Despite significant development in selective crystallization of chiral compounds this method still lacks high efficiency. Here the authors describe an efficient enantiomer-selective magnetization strategy for quantitatively separating the crystals of conglomerates by using magnetic nano-splitters.

    • Xichong Ye
    • , Jiaxi Cui
    • , Bowen Li
    • , Na Li
    • , Rong Wang
    • , Zijia Yan
    • , Junyan Tan
    • , Jie Zhang
    •  &  Xinhua Wan
  • Nature Communications | Article | open

    Microgels combine the properties of flexible polymers and colloids, but effects which influence the individual properties are less known. Here the authors show that the properties of a microgel can change from colloidal-like in three dimensions to a flexible polymer under a confined environment.

    • A. Scotti
    • , S. Bochenek
    • , M. Brugnoni
    • , M. A. Fernandez-Rodriguez
    • , M. F. Schulte
    • , J. E. Houston
    • , A. P. H. Gelissen
    • , I. I. Potemkin
    • , L. Isa
    •  &  W. Richtering
  • Nature Communications | Article | open

    Incorporation of self-healing and shape programming capabilities into rigid, structural composite is highly desirable yet challenging. Here, the authors report a nacre-mimetic composite obtained by infiltrating a switchable Diels-Alder network polymer into a scaffold of alumina capable of self-healing internal damage.

    • Gaolai Du
    • , Anran Mao
    • , Jinhong Yu
    • , Jingjing Hou
    • , Nifang Zhao
    • , Jingkai Han
    • , Qian Zhao
    • , Weiwei Gao
    • , Tao Xie
    •  &  Hao Bai
  • Nature Communications | Article | open

    Organic cocrystals have interesting properties owing to synergistic effects of the individual components but development of effective growth methods for molecular cocrystals is still in its primary stage. Here the authors demonstrate a sublimation method which allows growing organic cocrystals with controlled morphology.

    • Xin Ye
    • , Yang Liu
    • , Qing Guo
    • , Quanxiang Han
    • , Chao Ge
    • , Shuangyue Cui
    • , Leilei Zhang
    •  &  Xutang Tao
  • Nature Communications | Article | open

    Self-assembly of carbohydrates play an integral part in the design of higher ordered structures, but is limited to amphiphiles where the carbohydrate is covalently bound to a hydrophobic tail. Here the authors show that sugars direct the self-assembly of insoluble curcumin and the formation of well-defined capsules.

    • Sandy Wong
    • , Jiacheng Zhao
    • , Cheng Cao
    • , Chin Ken Wong
    • , Rhiannon P. Kuchel
    • , Sergio De Luca
    • , James M. Hook
    • , Christopher J. Garvey
    • , Sean Smith
    • , Junming Ho
    •  &  Martina H. Stenzel
  • Nature Communications | Article | open

    High mass loading and fast charge transport are two crucial but often mutually exclusive characteristics of pseudocapacitors. Here, the authors address this challenge by making use of block copolymer phase separation in the synthesis of porous carbon fibres as carbon supports for pseudocapacitors.

    • Tianyu Liu
    • , Zhengping Zhou
    • , Yichen Guo
    • , Dong Guo
    •  &  Guoliang Liu
  • Nature Communications | Article | open

    Bacterial cellulose (BC) is a ubiquitous biomaterial, but functionalization relies on modification processes which have low reaction efficiency and can cause pollution. Here the authors develop an environmental friendly in-situ fermentation method using fluorescein labelled glucose to produce fluorescent BC.

    • Minghong Gao
    • , Juan Li
    • , Zixian Bao
    • , Moudong Hu
    • , Rui Nian
    • , Dexin Feng
    • , Dong An
    • , Xing Li
    • , Mo Xian
    •  &  Haibo Zhang
  • Nature Communications | Article | open

    Organic luminescent materials are often used in modern technologies, but aggregation induced quenching caused by planar aromatic structures hampers their applicability. Here, the authors demonstrate a facile co-assembly method for luminescent cocrystals and protection with hydrophilic PEO chains which allow good dispersibility in water.

    • Yinjuan Huang
    • , Jie Xing
    • , Qiuyu Gong
    • , Li-Chuan Chen
    • , Guangfeng Liu
    • , Changjiang Yao
    • , Zongrui Wang
    • , Hao-Li Zhang
    • , Zhong Chen
    •  &  Qichun Zhang
  • Nature Communications | Article | open

    The discovery of new covalent organic framework (COF) topologies is often led by trial-and-error experiments. Here, the authors present a methodology for high throughput construction of COFs based on a materials genomics strategy and demonstrate the synthesis of the generated 2D and 3D-COFs.

    • Youshi Lan
    • , Xianghao Han
    • , Minman Tong
    • , Hongliang Huang
    • , Qingyuan Yang
    • , Dahuan Liu
    • , Xin Zhao
    •  &  Chongli Zhong
  • Nature Communications | Article | open

    3D covalent organic frameworks (COF) show interesting hierarchical arrangements of nanopores and open sites but their synthesis remains challenging. Here the authors report a fluorescent AIEgen-based 3D COF and demonstrate application as a coating material for white LEDs and for sensing of picric acid

    • Huimin Ding
    • , Jian Li
    • , Guohua Xie
    • , Guiqing Lin
    • , Rufan Chen
    • , Zhengkang Peng
    • , Chuluo Yang
    • , Baoshan Wang
    • , Junliang Sun
    •  &  Cheng Wang
  • Nature Communications | Article | open

    Tuning the mechanical properties of extracellular matrix is of great interest in tissue engineering but spatial control over stiffness in hydrogels has been demonstrated in two dimensions only. Here the authors developed a layer-by-layer printing technique which uses oxygen inhibition to control the heterogeneous stiffness in 3D printed structures.

    • Hang Yin
    • , Yonghui Ding
    • , Yao Zhai
    • , Wei Tan
    •  &  Xiaobo Yin
  • Nature Communications | Article | open

    Monodisperse biaxial colloidal particles are used as model systems to understand the phase behavior of biaxial molecules but high-quality biaxial colloids are limited. Here the authors describe gram-scale synthesis of uniform biaxial colloidal cuboids and their assembly into mesophasic structures.

    • Yang Yang
    • , Guangdong Chen
    • , Srinivas Thanneeru
    • , Jie He
    • , Kun Liu
    •  &  Zhihong Nie
  • Nature Communications | Article | open

    Gels filtering particles by interactions are a goal of nanotechnology; this is difficult when particles are larger than the mesh of the gel. Here, the authors present an equilibrium mechanism where binding dynamics of crosslinks are affected by interacting particles so that particles experience enhanced diffusion.

    • Carl P. Goodrich
    • , Michael P. Brenner
    •  &  Katharina Ribbeck
  • Nature Communications | Article | open

    Superplasticity enables processing on hard-to-work solids but superelastic deformation, especially in a single-crystal-to-single-crystal manner, was not demonstrated for organic crystals so far. Here the authors demonstrate a single-crystal-to-single-crystal superplasticity in a crystal of N,N-dimethyl-4-nitroaniline.

    • Satoshi Takamizawa
    • , Yuichi Takasaki
    • , Toshiyuki Sasaki
    •  &  Noriaki Ozaki
  • Nature Communications | Article | open

    Covalent organic frameworks (COFs) find increasing application as sensor material, but fast switching solvatochromism was not realized. Here the authors demonstrate that combination of electron-rich and -deficient building blocks leads to COFs which fast and reversibly change of their electronic structure depending on the surrounding atmosphere.

    • Laura Ascherl
    • , Emrys W. Evans
    • , Matthias Hennemann
    • , Daniele Di Nuzzo
    • , Alexander G. Hufnagel
    • , Michael Beetz
    • , Richard H. Friend
    • , Timothy Clark
    • , Thomas Bein
    •  &  Florian Auras
  • Nature Communications | Article | open

    Water uptake of natural polymers is accompanied by swelling and changes in the internal structure of the polymeric system but the exact mechanism of water-uptake and swelling remained unknown. Here the authors use atom-scale simulations to identify a molecular mechanism which is responsible for hysteresis in sorption-induced swelling in natural polymers.

    • Mingyang Chen
    • , Benoit Coasne
    • , Robert Guyer
    • , Dominique Derome
    •  &  Jan Carmeliet
  • Nature Communications | Article | open

    Liquid crystalline elastomers (LCE) exhibit shape transformation when subjected to various stimuli, but the achievable thickness of LCE films is limited. Here the authors demonstrate arbitrarily thick LCE films that are continuous in composition and maintain the director orientation, prescribed into the material.

    • Tyler Guin
    • , Michael J. Settle
    • , Benjamin A. Kowalski
    • , Anesia D. Auguste
    • , Richard V. Beblo
    • , Gregory W. Reich
    •  &  Timothy J. White
  • Nature Communications | Article | open

    Subtractive manufacturing of microstructures is important for many applications, yet photoresists for 3D laser lithography allow only removal after development under harsh cleavage conditions. Here, the authors introduce a set of chemoselective cleavable photoresists allowing the orthogonal cleavage of microstructures under mild conditions.

    • David Gräfe
    • , Andreas Wickberg
    • , Markus Michael Zieger
    • , Martin Wegener
    • , Eva Blasco
    •  &  Christopher Barner-Kowollik
  • Nature Communications | Article | open

    Nitrogen-vacancy (NV) centers in diamonds are used for quantum sensing but NV centers are not sensitive to parameters such as temperature, pressure and biomolecules. Here the authors propose a scheme based on a magnetic nanoparticle docked responsive hydrogel which acts as a transducer between the particles and the diamond.

    • Ting Zhang
    • , Gang-Qin Liu
    • , Weng-Hang Leong
    • , Chu-Feng Liu
    • , Man-Hin Kwok
    • , To Ngai
    • , Ren-Bao Liu
    •  &  Quan Li
  • Nature Communications | Article | open

    Polymers cross-linked with dynamic bonds can switch the phase from solid to fluid upon stimulus but return quickly to the solid state once the stimulus is removed. Here the authors report a light triggered permanent solid to fluid transition at room temperature with inherent spatiotemporal control in either direction

    • Brady T. Worrell
    • , Matthew K. McBride
    • , Gayla B. Lyon
    • , Lewis M. Cox
    • , Chen Wang
    • , Sudheendran Mavila
    • , Chern-Hooi Lim
    • , Hannah M. Coley
    • , Charles B. Musgrave
    • , Yifu Ding
    •  &  Christopher N. Bowman
  • Nature Communications | Article | open

    Stretchable conductors are important for further developments in the electronics industry, but improving the deformability when maintaining the high-level conductivity is still challenging. Here the authors demonstrate a ternary self-healing silver nanowire/polymer network as high-performance stretchable conductor.

    • Pin Song
    • , Haili Qin
    • , Huai-Ling Gao
    • , Huai-Ping Cong
    •  &  Shu-Hong Yu
  • Nature Communications | Article | open

    Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs.

    • Guiyang Zhang
    • , Xinle Li
    • , Qiaobo Liao
    • , Yanfeng Liu
    • , Kai Xi
    • , Wenyu Huang
    •  &  Xudong Jia
  • Nature Communications | Article | open

    Perylene bisimides (PBI) exhibit interesting photophysical and self-assembly properties but detailed understanding of the correlation between packing motif and spectroscopic properties is lacking. Here the authors report on self-assembling of PBIs in liquid crystalline phases to give aggregates with J- and H-type coupling contribution between the chromophores.

    • Stefanie Herbst
    • , Bartolome Soberats
    • , Pawaret Leowanawat
    • , Matthias Stolte
    • , Matthias Lehmann
    •  &  Frank Würthner
  • Nature Communications | Article | open

    Stabilization of covalent organic frameworks (COFs) by post-synthetic locking is a powerful tool to push the limits of COF utilization. Here the authors demonstrate a sulfur-assisted conversion of an imine-linked COF into a thiazole-linked COF, with retention of crystallinity and porosity, allowing for direct imaging of defects in COFs.

    • Frederik Haase
    • , Erik Troschke
    • , Gökcen Savasci
    • , Tanmay Banerjee
    • , Viola Duppel
    • , Susanne Dörfler
    • , Martin M. J. Grundei
    • , Asbjörn M. Burow
    • , Christian Ochsenfeld
    • , Stefan Kaskel
    •  &  Bettina V. Lotsch
  • Nature Communications | Article | open

    Using ions of one polarity to form functional layers on surfaces is usually challenging because of counter ions which are inevitably present in the condensed phase. Here the authors demonstrate accumulation of mass-selected anions and neutral molecules from the gas phase to form a self-organizing liquid-like layer on a surface.

    • Jonas Warneke
    • , Martin E. McBriarty
    • , Shawn L. Riechers
    • , Swarup China
    • , Mark H. Engelhard
    • , Edoardo Aprà
    • , Robert P. Young
    • , Nancy M. Washton
    • , Carsten Jenne
    • , Grant E. Johnson
    •  &  Julia Laskin