Inter-organelle communication

Organelles have been traditionally viewed as individual entities with defined composition and organization that endow them with specialized functions. However, it is now apparent that intracellular membrane compartments engage in extensive communication, either indirectly, or directly through membrane contacts. Inter-organelle communication is essential for cell function and for tissue and organismal homeostasis, as it regulates processes from lipid metabolism to cell death.

This collection of research articles, reviews and protocols from across the Nature Research group showcases the latest progress in understanding the mechanisms and functions of inter-organelle communication. It also highlights how the recent characterization of membrane contact sites has established a new framework to study cellular processes in the context of physiology and disease.

Research articles

Reviews and protocols