Tumour progression is not only dictated by events within tumour cells, but also by whether the surrounding niche is permissive to growth at all stages of disease. Tumours develop in a complex tissue network to which many different cell types are recruited, and this constitutes the tumour microenvironment (TME). The interactions between cancer cells and cells in the TME can lead to immune evasion, angiogenesis, hypoxia and invasion, all of which can shape tumour progression and response to treatment. This poster illustrates the influence of the TME on cancer progression and metastasis, and the different therapeutic opportunities that interactions between cancer cells and the TME can offer.
The Poster is freely available thanks to support from Fluidigm
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