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Cervical cancer is the fourth most common and has the fourth highest mortality rate among all cancers in people assigned female at birth. As this cancer is typically preventable with routine screening, most cases are diagnosed in populations without adequate access to preventative healthcare. Virtually all cases of cervical cancer involve infection with the human papillomavirus (HPV), and, despite HPV screening and prophylactic HPV vaccination efforts, the global incidence of cervical cancer remains high. Currently, progress is being made toward developing therapeutic HPV vaccines that stimulate cell-mediated immunity rather than neutralizing antibodies.
This Collection welcomes original research on cervical cancer and HPV infection, including their epidemiology, diagnosis, treatment, and prevention.