Collection 

Stromal cells in immunology

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Stromal cells are found in almost all tissues and comprise a variety of cell types, including mesenchymal stem cells, blood endothelial cells, and lymphatic endothelial cells. Aside from supporting the function of the parenchyma in their respective organs, they also play a major role in immune function. Stromal cells are critical for suppressing excessive immune responses, inhibiting T and B cells via anti-inflammatory factors. Conversely, they can also stimulate the immune response by secreting pro-inflammatory cytokines and chemokines.

This Collection will highlight original research exploring the pivotal roles and complex immunoregulatory effects of stromal cells throughout the body.

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Real fluorescence microscopic view of Mesenchymal stem cells in red and blue fluorescence

Editors

  • Chihiro Akazawa  &

    Chihiro Akazawa

    Juntendo University Graduate School of Medicine, Japan

  • Masoud H. Manjili

    Masoud H. Manjili

    Virginia Commonwealth University School of Medicine, USA

Articles will be displayed here once they are published.