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APS HIGHLIGHTS 2010
Covering the latest in pharmacology, Acta Pharmacologica Sinica is proud to present some of the most accessed articles during 2010, as chosen by the Editor. These articles highlight the latest within pharmacology and the life sciences, covering a range of topics including cardiovascular medicine, neuroscience, cancer, immunology, molecular cell biology, endocrinology, chemistry, and methods and protocols.
Reviews
MicroRNAs: a novel class of potential therapeutic targets for cardiovascular diseases FREE
Zhen-wei Pan, Yan-jie Lu and Bao-feng Yang
Acta Pharmacol Sin 31: 1-9; advance online publication, December 7, 2009; doi:10.1038/aps.2009.175
Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia FREE
Ying Wang, Lu-qi Huang, Xi-can Tang and Hai-yan Zhang
Acta Pharmacol Sin 31: 649-664; doi:10.1038/aps.2010.46
Autophagic pathways as new targets for cancer drug development FREE
Bo Liu, Yan Cheng, Qian Liu, Jin-ku Bao and Jin-Ming Yang
Acta Pharmacol Sin 31: 1154-1164; advance online publication, August 9, 2010; doi:10.1038/aps.2010.118
Type I natural killer T cells: naturally born for fighting FREE
Jin-quan Tan, Wei Xiao, Lan Wang and Yu-ling He
Acta Pharmacol Sin 31: 1123-1132; advance online publication, August 9, 2010; doi:10.1038/aps.2010.119
Articles
Differentiation of embryonic stem cells into hepatocytes that coexpress coagulation factors VIII and IX FREE
Jun Cao, Chang-zhen Shang, Li-hong Lü, De-chuan Qiu, Meng Ren, Ya-jin Chen and Jun Min
Acta Pharmacol Sin 31: 1478-1486; advance online publication, October 18, 2010; doi:10.1038/aps.2010.100
High dosage of Exendin-4 increased early insulin secretion in differentiated beta cells from mouse embryonic stem cells FREE
Hua Li, Amy Lam, Ai-min Xu, Karen Sl Lam and Sookja Kim Chung
Acta Pharmacol Sin 31: 570-577; advance online publication, April 26, 2010; doi:10.1038/aps.2010.38
Expression of a dominant-negative Rho-kinase promotes neurite outgrowth in a microenvironment mimicking injured central nervous system FREE
Ping Yang, Hui-zhong Wen and Jin-hai Zhang
Acta Pharmacol Sin 31: 531-539; advance online publication, April 12, 2010; doi:10.1038/aps.2010.35
Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats FREE
Bo-bo Chang, Lin Zhang, Wan-wen Cao, Yuan Cao, Wen-liang Yang, Yan Wang, Yuan-cheng Chen and Xiao-quan Liu
Acta Pharmacol Sin 31: 638-646; advance online publication, April 5, 2010; doi:10.1038/aps.2010.27
Krüppel-like factor 4 interacts with p300 to activate mitofusin 2 gene expression induced by all-trans retinoic acid in VSMCs FREE
Rui Zhang, Mei Han, Bin Zheng, Ying-jie Li, Ya-nan Shu and Jin-kun Wen
Acta Pharmacol Sin 31: 1293-1302; advance online publication, August 16, 2010; doi:10.1038/aps.2010.96