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Twistronics is a rapidly developing field in the area of two-dimensional materials. By simply adjusting the angle – or twist – between layers of two-dimensional materials, one can control the electrical properties of the complete system to produce incredible effects such as switching between non-conducting and superconducting states. This Collection gather research articles that focus on the emerging field of Twistronics, spanning from the investigation of new materials/methods to novel applications, as well as related insights into van der Waals heterostructures, that further our understanding.