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Helicobacter pylori is a gram-negative bacterium that infects the stomach lining; it can cause gastrointestinal conditions such as gastritis or ulcers and can lead to an increased risk of stomach cancer. It is transmitted through person-to-person contact, and factors like poor hygiene and contaminated food or water contribute to its spread. Diagnosis of H. pylori infections can be done by a variety of methods, most commonly a stool test, but also breath tests, blood tests, and endoscopic biopsies. Although many H. pylori infections are asymptomatic and can be harmless, the adaptations of this bacteria mean that it’s very capable of evading the human immune system and can be difficult to treat. Infections causing health problems may respond to treatments such as antibiotics and acid-suppressing medication, however antibiotic resistance is on the rise.
This Collection invites original research that investigates the causes, diagnosis or treatment of Helicobacter infections.