Series


Series on Cancer Cell Biology

Cancer is a disease of deregulated cellular behaviour, as oncogenic alterations endow cancer cells with properties that allow them to hijack normal cellular processes resulting in unlimited proliferation, evasion of death signals and spread to distant sites through the process of metastasis. The mechanisms of tumour suppression and of cancer initiation and propagation, as well as the attributes that permit cancer cells to escape the confines of the primary tumour and to metastasize, are areas of intense research. Nature Cell Biology presents a series of review and perspective articles by leading scientists, discussing recent advances and challenges in cancer cell biology. These pieces were published as part of the series over several months and are accompanied by an online library of related research papers from Nature Cell Biology and other Nature journals.

Editorial

Focusing on the cell biology of cancer

DOI: 10.1038/ncb2667; Nature Cell Biology 15, 1; (2013)

Reviews

p53 mutations in cancer

Patricia A. J. Muller and Karen H. Vousden

DOI: 10.1038/ncb2641; Nature Cell Biology 15, 2–8; (2013)

Tracing the cellular origin of cancer

Cédric Blanpain

DOI: 10.1038/ncb2657; Nature Cell Biology 15, 126–134; (2013)

Control of metastatic progression by microRNA regulatory networks

Nora Pencheva and Sohail F. Tavazoie

DOI: 10.1038/ncb2769; Nature Cell Biology 15, 546–554; (2013)

Perspective

Cancer stem cells: The challenges ahead

Jan Paul Medema

DOI: 10.1038/ncb2717; Nature Cell Biology 15, 338–344; (2013)