Regulatory T cells
- Submission status
- Open
- Submission deadline
Regulatory T cells are a critical part of the immune system, preventing autoimmune diseases and limiting chronic inflammatory diseases like asthma and inflammatory bowel disease. However, these immunosuppressive cells can also prevent the establishment of protective immune responses and limit anti-tumour immunity. Regulatory T cells can induce suppression in several ways, including via inhibitory cytokines, cytolysis, metabolic disruption, and modulation of dendritic-cell maturation or function. However, the relationship between these mechanisms, as well as their relative importance, remains unclear.
This Collection welcomes original research on all aspects of regulatory T cells, including their development, their function, and their roles in conditions and diseases such as autoimmunity and cancer.
Editors
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Khalid Muhammad, PhD
Associate Professor, Department of Biology, College of Science, UAE University, Al Ain, UAE.
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Shresh Pathak, PhD
Assistant Professor, Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA Assistant Professor, Department of Otolaryngology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA
