Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
This new web focus from Cell, Death & Differentiation highlights some of the latest research and thinking on programmed necrosis (necroptosis) from some of the world's most recognised experts. Necroptosis is a form of programmed cell death that depends on the activation of receptor interacting protein kinase-1 (RIPK1) and RIPK3 by receptors such as tumor necrosis factor (TNF) receptor-1. This focus reflects the current interest in this important and fast developing research area - an area which has strong potential to make a significant impact on the development of new treatments for multiple human diseases.