Imaging of cells and cellular dynamics
Recent advances in both the hard- and software used in live cell imaging allow us to observe cell structure and dynamics in never before seen detail and enable new quantitative analysis of dynamic intracellular processes. Such detailed observation frequently reveals new insights hidden from lower resolution or biochemical approaches that average data over large cell populations. This Collection draws together new research from across the life sciences showcasing innovations in cell imaging methodologies and image analysis techniques, and how these are put into practice.
Editors
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Andrew Clayton
Swinburne University of Technology, Australia
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Florian Rehfeldt
University of Bayreuth, Germany
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Torsten Wittmann
University of California, USA
Andrew Clayton is a biophysicist who develops advanced microscopy techniques in order to quantify macromolecular interactions and dynamics in living cells. He was educated at the University of Melbourne (B.Sc (hons, H1), PhD) and is currently Professor of Bio-photonics at Swinburne University of Technology in Melbourne. He has held appointments at the University of Melbourne, Max-Planck Institute and Ludwig Institute for Cancer Research. Prof Clayton has been an Editorial Board Member for Scientific Reports since 2014.
Florian Rehfeldt holds a PhD in Physics from TU Munich, Germany and subsequently moved to University of Pennsylvania in Philadelphia, USA. Following this postdoctoral stay, he went as a group leader to University of Göttingen, Germany and since 2019 he is a tenured senior scientist at the University of Bayreuth, Germany. His research interests in biophysics include in particular the mechanical interactions of cells and the extracellular matrix. One focus is on structure and dynamics of the cytoskeleton and the nucleus to elucidate how mechanical cues from the outside are integrated into biochemical signaling and eventually affect cell fate. Dr Rehfeldt has been an Editorial Board Member for Scientific Reports since 2014.
Torsten Wittmann is a Professor in the Department of Cell and Tissue Biology at the University of California, San Francisco. Research in the Wittmann lab focusses on how the microtubule cytoskeleton organizes intracellular structure and controls complex cell dynamics such as migration, polarity, and division that are critical to normal and pathological cell biology. Prof. Wittmann received his PhD from the University of Heidelberg / European Molecular Biology Laboratory in 1999 and since then has worked on many aspects of intracellular dynamics utilizing advanced live cell microscopy and optogenetics approaches. Prof Wittmann has been an Editorial Board Member for Scientific Reports since 2013.
