Barrier function and the immune system
- Submission status
- Open
The immune system’s front line of defence against pathogens are the barriers presented by surfaces including the skin, gut mucosa and airway epithelium. Whilst providing a physical barrier through a highly structured arrangement of cells, tissues also present a chemical barrier in the form of secretions that prevent pathogenic attachment. Pathogens interact with these barriers through specific receptors and molecular pathways and disruption of barrier function is one of the major triggers of the inflammatory response. Impaired barrier function is also associated with autoimmune diseases, such as gastrointestinal disease, and is therefore a target for the development of novel treatment strategies.
This Collection welcomes manuscripts that increase our understanding of the role and mechanisms of barrier function in the immune response in a range of tissues, study how this response is modulated by interactions with various pathogens or in autoimmune diseases, and explore novel treatment strategies that restore or regulate barrier function.
Editors
-
Marina Casalino-Matsuda
Northwestern University, USA
-
Brice Sperandio
INSERM, France
Submitting a paper for consideration
To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Barrier function and the immune system" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.
Accepted papers are published on a rolling basis as soon as they are ready.
In addition to papers on Barrier function and the immune system, Scientific Reports welcomes all original research in the field of Immunology. To browse our latest articles in Immunology, click here.
