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Owning to advanced maternal and paternal ages, changes in life style habits and environmental factors, the past decades have seen a rise in infertility rates worldwide. Today, approximately every sixth couple of reproductive age encounter difficulties in conceiving. In this context, the use of assisted reproductive strategies to facilitate conception is also increasing, with an estimated annual growth rate of 5-10%. This Collection brings together some of our latest reports on technological developments in assisted reproduction and obstetrical outcomes of such procedures.