Autoimmune diseases
- Submission status
- Closed
- Submission deadline
Autoimmune diseases are characterised by the immune system’s attack on the body’s own tissues. These conditions affect an increasing number of people worldwide, predominantly women. Loss of tolerance to self-antigens can occur in virtually all of the body’s organs and systems, including digestive (e.g., type 1 diabetes, inflammatory bowel disease), endocrine (e.g., Grave’s disease, Addison’s disease), and neurological (e.g., multiple sclerosis, autoimmune epilepsy), as well as connective tissue (e.g., rheumatoid arthritis, spondyloarthritis). While autoimmunity has been linked to genetic and epigenetic factors as well as to a range of environmental triggers such as pathogens and drugs, the underlying causes of many of these conditions remains incompletely understood. This Collection will highlight articles on all aspects of autoimmune diseases, including their etiology, epidemiology, diagnosis, and treatment.
Editors
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Gamal Badr
Faculty of Science, Assiut University, Egypt.
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Janine Bilsborough
F. Widjaja Inflammatory Bowel Disease Institute, USA
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Coziana Ciurtin
University College London, London, UK
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George C. Tsokos
Division of Rheumatology and Clinical Immunology, Beth Israel Deaconess Medical Center, USA
Gamal Badr is a Professor of Immunology at Assiut University. Their research interests are focused on molecular immunology, diabetic wound healing, cell signalling, and molecular cell biology. Professor Badr has been an Editorial Board Member for Scientific Reports since 2019.
Janine Bilsborough is an Associate Professor and Director of the IBD3 Drug Discovery and Development unit for Inflammatory Bowel Disease (IBD) at Cedars-Sinai Medical Center in Los Angeles. She is an immunologist with a focus on the discovery of new therapeutic targets for IBD using the principles of precision medicine to optimise patient outcomes.Professor Bilsborough has been an Editorial Board Member for Scientific Reports since 2019.
Coziana Ciurtin is an Associate Professor at University College London and Consultant in Adolescent and Adult Rheumatology at University College London Hospital. Her major research interests are related to investigating the impact of sex and puberty determinants on the functions of the immune system and molecular biomarker stratification of young people with autoimmune rheumatic diseases for personalised treatment approaches. Dr Ciurtin has been an Editorial Board Member for Scientific Reports since 2020.
George C. Tsokos is a Professor of Medicine at Harvard Medical School and Chief of Rheumatology and Clinical Immunology at the Beth Israel Deaconess Medical Center. He has led the field of molecular abnormalities on immune cells in patients with SLE and has identified previously unknown pathways that have served as the basis for novel treatments currently in various phases of development. More recently he has launched studies to decipher the interaction between immune and kidney resident cells and to identify local processes that enable renal injury. Professor Tsokos has been an Editorial Board Member for Scientific Reports since 2019.
