Articles in 2016

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  • The clinical impact of checkpoint inhibitors and their anticipated position as linchpins of future cancer immunotherapy regimens has driven a wave of dealmaking. In this feature, we chart the development progress and major deals for the leading checkpoint inhibitors.

    • Biopharma Dealmakers
    News Feature
  • A trend toward outsourcing early-stage R&D and thriving capital markets over the past few years have helped platform biotechs remain independent and able to ink creative deals with pharma companies.

    • Chris Morrison
    News Feature
  • Exicure is pioneering the development of spherical nucleic acid technology as a promising avenue of therapeutic development to strengthen and prolong the body’s natural immune defenses against a wide range of cancers.

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  • Plasticell is leveraging its innovative combinatorial screening technology for a broad range of cell and gene therapy applications, whereas spin-out Progenitor Therapeutics focuses on small-molecule regenerative drug discovery.

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  • With its innovative fusion cancer vaccine that greatly enhances the target specificity of T cells, Tokyo-based CyTIX is poised to take advantage of the biopharma industry’s increasing interest in next-generation cancer vaccines.

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  • BeyondSpring Pharmaceuticals’ plinabulin demonstrates a multifaceted approach that targets immune and vascular aspects of tumor growth, resulting in immune-enhancing effects.

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  • Trianni has developed transgenic immunoglobulin mice capable of expressing the full human antibody repertoire, ideal for the discovery of new therapeutic antibody candidates.

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  • Precision BioSciences is harnessing its next-generation genome editing platform, ARCUS, to develop a pipeline of cell-based immunotherapies for cancer and autoimmune disease, as well as gene therapies for rare genetic disorders. The company is looking for uniquely suited partners to aid in these efforts.

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