Abstract
Steel is prone to corrosion induced by chloride ions, which is a serious threat to reinforced concrete structures, especially in marine environments. In this work, we report a novel capsule-based self-recovery system that utilizes chloride ions as a trigger. These capsules, which are functionalized via a smart response to chloride ions, are fabricated using a silver alginate hydrogel that disintegrates upon contact with chloride ions and thereby releases the activated core materials. The experimental results show that the smart capsules respond to a very low concentration of chloride ions (0.1 wt%). Therefore, we believe that this novel capsule-based self-recovery system will exhibit a promising prospect for self-healing or corrosion inhibition applications.
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Introduction
Microencapsulation is an increasingly important technique that has been applied in many fields, such as self-healing materials1,2,3, drug delivery4,5,6, food preservation7,8,9, phase change materials10,11 and fragrance release12,13. It is believed that encapsulation technology is a burgeoning research area for self-healing materials and such technology can heal some cracks which are difficult to repair due to inaccessibility, as well as the cost is very low. However, a significant drawback in current capsule-based self-healing technology is that it is difficult to ensure all capsules will be broken by cracks (Fig. S1a), this depends on the interface bonding strength between the capsule and the matrix, so the healing efficiency will be low.
In anti-corrosion field, as we know, steel bars in reinforcement concrete are prone to corrosion induced by chloride ions, especially the reinforced concrete structure in marine environments14. The most commonly adopted strategy to solve this problem is to mix a corrosion inhibitor into concrete. Unfortunately, during the fabrication process of cement slurry, much of the corrosion inhibitor is lost, because of its dissolution and diffusion. It is a feasible method to embed capsules encapsulated corrosion inhibitor substance into matrix to solve the problem. When cracks appear, the capsules will be broken under stress to release the core materials. However, it is also not guaranteed that the capsules will function properly under a mechanical stress trigger. Furthermore, chloride ions can spread through many nano-cracks and channels that exist in the concrete matrix without the formation of micro-cracks (Fig. S1b); thus, when the rebars have been corroded, the capsules may still not start to work. In view of this, specifically, chloride ions will be a desirable trigger in a chloride-attack environment. Therefore, it is necessary to fabricate a kind of smart capsule which can be responsive to chloride ions, this concept can overcome these drawbacks. Many papers have reported a range of stimuli responsive capsules that disintegrate when exposed to physical15,16,17, biological18, chemical19,20 and combination triggers21. However, to the best of our knowledge, chloride ions stimuli responsive self-recovery system has not been reported yet. In the present work, we also demonstrate its potential application in cementitious materials.
Chloride ions provide a stable trigger for responsive capsules. A facile method is to fabricate responsive materials containing metal ions (such as Ag+, Pb2+) which can be precipitated with chloride ions to participate the wall formation of capsules. When these smart responsive capsules contact with chloride ions, the metal ions will be extracted out to disintegrate the capsules (Fig. 1a).
Alginate is a natural anionic polymer acquired from brown algae and has been extensively utilized for biomedical applications22. Sodium alginate can be crosslinked with many metal ions (such as Ca2+) to form hydrogel. In this experiment, Ag+ is chosen to be coordinated with alginate to form the wall materials of capsules, silver alginate (Ag-alg) can also form a characteristic “egg-box” structure23. Each alginate molecular chain can be linked with other chains, causing the formation of a three-dimension gel network (Fig. 1b)24, which has enough strength to form the wall.
Results
A range of methods have been utilized to fabricate alginate capsules including microfluidics25,26,27, internal gelation28,29 and orifice solid bath. In this work, Ag-alginate capsules are fabricated using the orifice solid bath method (Fig. S2)30. This approach is a facile synthesis and low cost technique. Its sole requirements are to mix core materials with sodium alginate solution, in addition to encapsulating aqueous substances, if the core materials are oil, surfactant is needed. After stirring, a syringe is used to extract the emulsion and then squeeze the emulsion out drop by drop, the droplets form capsules gelled by AgNO3 solution, the Ag-alginate capsules with oil cores are obtained.
Figure 2a shows the images of the Ag-alginate capsules. Figure 2b illustrates the magnified microscopic image of Ag-alginate capsules. The average size of capsules is around 2.5 mm. When the Ag-alginate capsules were added with several drops of NaCl 3.5 wt% (the concentration of NaCl in seawater) aqueous solution, the capsules were collapsed entirely in around 1 minute (Fig. 2c). The chloride ions triggering process was recorded in a movie (Supplementary movie 1).
Figure S3 shows the FTIR spectra of Na-alg and Ag-alg compounds. In the spectrum of Na-alg, the stretching vibrations peak of O-H is at 3268 cm−1 31 and the adjacent weak peak 2918 cm−1 should be assigned to C–H stretching vibrations of the methyne groups. The C-O-C stretching vibrations absorption brand of saccharide structure is at 1024 cm−1 32. The absorption bands for the symmetric and asymmetric vibrations of carboxylate anions are 1399 cm−1 and 1568 cm−1, respectively33. Comparing the two spectra, it is clear to find the absorption peak at 1568 cm−1 shifted to 1598 cm−1 in Ag-alg and the absorption intensity of the peak at 1411 cm−1 becomes stronger than the peak at 1399 cm−1. These results indicate the binding of Ag with funtional groups contained O34. Figure S4 shows the size distributions of Ag-alg beads and Ag-alg capsules. The capsules are uniform, the size distributions both are narrow and the average diameters are 2.4 mm and 2.5 mm, respectively.
FESEM (field environment scanning electron microscope) was employed to display the morphological features of the Ag-alginate capsule after being freeze dried (Fig. S5a). The porous structure of the surface is observable (Fig. S5b) for the evaporation of water in hydrogel. Figure S5c shows the image of a capsule that was exposed to chloride ions. It is clear that the responsive capsule was collapsed entirely, proving the Ag-alginate capsules can be triggered by chloride ions. Figure S5d shows the surface of the capsule after being triggered, compared to Figure S5b, the porous structure has disappeared. The elements analysis was carried out using energy dispersive X-ray spectroscopy (EDS) measurement, which identified the presence of the C, O, Na and Ag elements. the EDS elemental mapping indicated these elements were uniformly distributed on the surface of Ag-alg capsule (Fig. S6). After the triggering process, the EDS elemental mapping and element analysis were showed in Figure S7. It is noteworthy that the distribution of Ag became sparse for the disintegration of the Ag-alg capsule.
An alternative analysis is necessary for obtaining the chemical valence information of Ag. The XPS (X-ray photoelectron spectroscopy) survey spectrum is shown in Figure S8a. The peaks of Ag 3d5/2 and Ag 3d3/2 are identified at 368.4 eV and 374.5 eV, respectively. The peaks of Ag 3d5/2 and Ag 3d3/2 can be further divided into peaks at 368.1, 369.0 eV and 374.0, 374.9 eV, respectively. The peaks at 368.1 and 374.0 eV could be attributed to Ag+ 35,36 from Ag2O or Ag-alg, whereas those at 369.0 and 374.9 eV could be ascribed to Ag(0)32 (Figure S8b).
We employ confocal laser scanning microscopy (CLSM) to demonstrate the chloride ions responsive process (Fig. 3a–f). The Ag-alg capsule was labeled with green fluorescent dye - FITC (fluorescein isothiocyanate). The capsule was added with some drops of 3.5 wt% NaCl solution and then the capsule collapsed. This gradual responsive process proceeds over 50 s. It is in accordance with the preceding responsive experiment. Figure S9 shows the triggering time of Ag-alginate capsules added with different concentration of NaCl solution. The concentration is 0.1 wt%, 1 wt%, 2 wt%, 3 wt%, 4 wt% respectively. Accordingly, the triggering time is 142, 96, 83, 71 and 62 seconds. This proves the Ag-alginate capsules can be triggered at low concentration of chloride ions, the NaCl concentration of seawater is 3.5 wt%, consequently, the capsules can be triggered in marine environments.
X-ray computed tomography (X-ray CT) is a promising non-destructive technique to demonstrate the inner morphology within non-optically transparent materials. Moreover this versatile characterization approach can offer reconstructing modeling of spatial characteristics and volume fraction in 3D37. X-ray CT was employed to detect concrete specimen embedded with chloride ions responsive Ag-alg capsules (Fig. S10). For much more visualized contrast, Ag-alg capsules were not freeze dried. The Ag-alginate capsules became smaller during the concrete specimen hydrated process for the loss of water molecules in the framework of Ag-alginate hydrogel. Figure 4a shows the concrete specimen embedded with Ag-alginate capsules, but not be soaked with NaCl solution, it is observable to identify the shrinkage hydrogel. Figure 4b depicts the concrete specimen exposed to chloride ions environment. It is clear that the capsules near the surface of concrete specimen have disappeared, leaving hollow pores. In X-ray CT 3D model, heavy metals like Ag have a strong absorbency for X-ray and appear as bright objects in 3D images. Compared with X-ray CT 3D images (Fig. 4c,d), the capsules near the surface of concrete specimen also have disappeared, the contrast is much more observable. (Supplementary movie 2 and movie 3)
Discussion
In this work, we have introduced a new concept: chloride ions responsive capsule-based self-recovery system. Compared to traditional mechanical stress responsive system, the advantageous features of it are as follows. First, it is difficult to insure the capsules can be broken under mechanical stress (Fig. S1a). On the contrary, chemical responsive capsules can overcome this drawback, when contact with chloride ions, the all capsules will be broken. Second, chloride ions can penetrate into concrete matrix through nano cracks and channels without micro cracks formation (Fig. S1b), the smart capsules can still be responsive to chloride ions without relying on cracks, this has been proved by X-ray CT test.
In summary, we have successfully fabricated smart chloride ions responsive capsules, first introduce them into cementitious materials and prove the capsules still can be responsive to chloride ions in concrete matrix. This new self-recovery system will reduce deleterious effect of chloride-attack and possesses high broken efficiency and sensitivity advantages. Therefore, we anticipate that this novel self-recovery system will be a promising candidate for building materials and prolong the life of construction and building materials, especially in marine environment.
Methods
Ag-alginate capsules fabrication method
1.5 wt% sodium alginate solution emulsified with methyl methacrylate (MMA) and sodium dodecyl benzene sulfonate (SDBS), MMA is the oil core, SDBS is surfactant, we use a syringe to squeeze the emulsion out drop by drop into solid bath - 1 mol·L−1 AgNO3. After 10 h, the solution was filtered to obtain the capsules, washed with deionized water for several times.
Chloride ions responsive concentration test
To pick up four Ag-alginate capsules on a piece of smooth glass, added with different concentration of NaCl solution, that is 1 wt%, 2 wt%, 3 wt%, 4 wt%, respectively, the solution volume all are 0.3 mL, dropped by syringe.
Confocal laser scanning Microscopy
CLSM experiments were adopted to show the process of capsule triggered by chloride ions. Chitosan is labeled by FITC under weak base circumstance (pH value is 9) and then to mix the labeled chitosan into sodium alginate solution, after the fabrication of capsule procedures, we obtain chloride ions responsive capsules labeled with FITC.
Concrete specimen embedded Ag-alginate capsules
10 g cement was added to 4 g water, the ratio of water to cement is 0.4. The slurry was added to 1 g (10 wt% of cement) Ag-alginate capsules. After 7days, one concrete specimen was tested by X-ray CT, the other concrete specimen was soaked into 20 wt% NaCl (high concentration of NaCl is adopted for saving experiment time) solution for 15days and then the soaked specimen was tested by X-ray CT.
Additional Information
How to cite this article: Xiong, W. et al. A novel capsule-based self-recovery system with a chloride ion trigger. Sci. Rep. 5, 10866; doi: 10.1038/srep10866 (2015).
References
White, S. R. et al. Autonomic healing of polymer composites. Nature 409, 794–797, (2001).
Jin, H. H. et al. Thermally Stable Autonomic Healing in Epoxy using a Dual-Microcapsule System. Adv. Mater. 26, 282–287, (2014).
Yuan, Y. C. et al. Self-healing polymeric materials using epoxy/mercaptan as the healant. Macromolecules 41, 5197–5202, (2008).
Upadhyay, U. M. et al. Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. Proc. Natl. Acad. Sci. U. S. A. 111, 16071–16076, (2014).
Ma, G. H. Microencapsulation of protein drugs for drug delivery: Strategy, preparation and applications. J. Control. Release 193, 324–340, (2014).
Abbaspourrad, A., Datta, S. S. & Weitz, D. A. Controlling Release From pH-Responsive Microcapsules. Langmuir 29, 12697–12702, (2013).
Peng, C. et al. Chemical composition, antimicrobial property and microencapsulation of Mustard (Sinapis alba) seed essential oil by complex coacervation. Food Chem. 165, 560–568, (2014).
Wang, Y. F. et al. Food preservation effects of curcumin microcapsules. Food Control 27, 113–117, (2012).
Filippidi, E., Patel, A. R., Bouwens, E. C. M., Voudouris, P. & Velikov, K. P. All-Natural Oil-Filled Microcapsules from Water-Insoluble Proteins. Adv. Funct. Mater. 24, 5962–5968, (2014).
Jin, Z. G., Wang, Y. D., Liu, J. G. & Yang, Z. Z. Synthesis and properties of paraffin capsules as phase change materials. Polymer 49, 2903–2910, (2008).
He, F., Wang, X. D. & Wu, D. Z. New approach for sol-gel synthesis of microencapsulated n-octadecane phase change material with silica wall using sodium silicate precursor. Energy 67, 223–233, (2014).
Hofmeister, I., Landfester, K. & Taden, A. pH-Sensitive Nanocapsules with Barrier Properties: Fragrance Encapsulation and Controlled Release. Macromolecules 47, 5768–5773, (2014).
Li, Y., Huang, Y. Q., Fan, H. F. & Xia, Q. Heat-Resistant Sustained-Release Fragrance Microcapsules. J. Appl. Polym. Sci. 131, 40053, (2014).
Zeng, L. W. & Song, R. X. Controlling chloride ions diffusion in concrete. Sci Rep. 3, 3359, (2013).
Seiffert, S. Small but Smart: Sensitive Microgel Capsules. Angew. Chem. -Int. Edit. 52, 11462–11468, (2013).
Narita, T., Takakura, H., Ogata, N., Kawakita, H. & Oishi, Y. Self-pulsation observed in pH-sensitive microcapsules. Chem. Commun. 49, 919–921, (2013).
Abbaspourrad, A., Carroll, N. J., Kim, S. H. & Weitz, D. A. Polymer Microcapsules with Programmable Active Release. J. Am. Chem. Soc. 135, 7744–7750, (2013).
Del Mercato, L. L. et al. Biological applications of LbL multilayer capsules: From drug delivery to sensing. Adv. Colloid Interface Sci. 207, 139–154, (2014).
Esser-Kahn, A. P., Odom, S. A., Sottos, N. R., White, S. R. & Moore, J. S. Triggered Release from Polymer Capsules. Macromolecules 44, 5539–5553, (2011).
Broaders, K. E., Pastine, S. J., Grandhe, S. & Frechet, J. M. J. Acid-degradable solid-walled microcapsules for pH-responsive burst-release drug delivery. Chem. Commun. 47, 665–667, (2011).
Gun, W. J. & Routh, A. F. Formation and Characterization of pH-Responsive Liquid Core Microcapsules. Langmuir 29, 12541–12548, (2013).
Lee, K. Y. & Mooney, D. J. Alginate: Properties and biomedical applications. Prog. Polym. Sci. 37, 106–126, (2012).
Poojari, R. & Srivastava, R. Composite alginate microspheres as the next-generation egg-box carriers for biomacromolecules delivery. Expert Opin. Drug Deliv. 10, 1061–1076, (2013).
Paques, J. P., van der Linden, E., van Rijn, C. J. M. & Sagis, L. M. C. Preparation methods of alginate nanoparticles. Adv. Colloid Interface Sci. 209, 163–171, (2014).
Yang, C. H. et al. Core-shell structure microcapsules with dual pH-responsive drug release function. Electrophoresis 35, 2673–2680, (2014).
Ma, M. L. et al. Core-Shell Hydrogel Microcapsules for Improved Islets Encapsulation. Adv. Healthc. Mater. 2, 667–672, (2013).
Ren, P. W., Ju, X. J., Xie, R. & Chu, L. Y. Monodisperse alginate microcapsules with oil core generated from a microfluidic device. J. Colloid Interface Sci. 343, 392–395, (2010).
Puguan, J. M. C., Yu, X. H. & Kim, H. Characterization of structure, physico-chemical properties and diffusion behavior of Ca-Alginate gel beads prepared by different gelation methods. J. Colloid Interface Sci. 432, 109–116, (2014).
Liu, L. et al. Preparation of monodisperse calcium alginate microcapsules via internal gelation in microfluidic-generated double emulsions. J. Colloid Interface Sci. 404, 85–90, (2013).
Dowling, M. B., Bagal, A. S. & Raghavan, S. R. Self-Destructing “Mothership” Capsules for Timed Release of Encapsulated Contents. Langmuir 29, 7993–7998, (2013).
Otari, S. V., Patil, R. M., Waghmare, S. R., Ghosh, S. J. & Pawar, S. H. A novel microbial synthesis of catalytically active Ag-alginate biohydrogel and its antimicrobial activity. Dalton T rans. 42, 9966–9975, (2013).
Ai, L. H., Yue, H. T. & Jiang, J. Environmentally friendly light-driven synthesis of Ag nanoparticles in situ grown on magnetically separable biohydrogels as highly active and recyclable catalysts for 4-nitrophenol reduction. J Mater. Chem. 22, 23447–23453, (2012).
Sharma, S., Sanpui, P., Chattopadhyay, A. & Ghosh, S. S. Fabrication of antibacterial silver nanoparticle-sodium alginate-chitosan composite films. Rsc Adv. 2, 5837–5843, (2012).
Ali, S. W., Rajendran, S. & Joshi, M. Synthesis and characterization of chitosan and silver loaded chitosan nanoparticles for bioactive polyester. Carbohydr. Polym. 83, 438–446, (2011).
Song, Y. X. et al. Synthesis, characterization and visible-light photocatalytic performance of Ag2CO3 modified by graphene-oxide. J. Alloy. Compd. 592, 258–265, (2014).
Wu, Q. M. et al. Electrocatalytic activity and stability of Ag-MnOx/C composites toward oxygen reduction reaction in alkaline solution. Electrochim. Acta 123, 167–175, (2014).
Mookhoek, S. D. et al. Applying SEM-Based X-ray Microtomography to Observe Self-Healing in Solvent Encapsulated Thermoplastic Materials. Adv. Eng. Mater. 12, 228–234, (2010).
Acknowledgements
The authors would like to acknowledge financial support provided by National Natural Science Foundation of China (No.51120185002/U1301241); and Collaborative Innovation Center for Advanced Civil Engineering Materials, Nanjing, P. R. China.
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F.X., N.X.H. and B.Q.D. conceived the project. W.X. performed the all experiments. W.X., J.N.T., G.M.Z., N.X.H. E.S. and W.X.F. all discussed the results, commented on and revised the manuscript.
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Xiong, W., Tang, J., Zhu, G. et al. A novel capsule-based self-recovery system with a chloride ion trigger. Sci Rep 5, 10866 (2015). https://doi.org/10.1038/srep10866
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DOI: https://doi.org/10.1038/srep10866
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