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Silver–polysaccharide nanocomposite antimicrobial coatings for methacrylic thermosets

A selection of abstracts of clinically relevant papers from other journals. The abstracts on this page have been chosen and edited by John R. Radford.


Preventing the dental biofilm on resin composites.


Travan A, Marsich E et al. Acta Biomaterialia 2011; 7: 337–346

An overarching aim is to develop an antimicrobial coating for the methacrylic thermoset BisGMA/TEGDMA, yet at the same time one that is not cytotoxic. A candidate material is silver. Among other properties, silver is antimicrobial and can form nanoparticles that have a large surface activity. These investigators have previously reported coating discs of BisGMA/TEGDMA with a polysaccharide film in order to immobilise accessible silver nanoparticles. Using such coated discs, they measured the antimicrobial efficacy against a strain of Pseudomonas aeruginosa and Staphylococcus aureus. They found that the bacterial strains were 'effectively inactivated' by the nanocomposite coating. The investigators also carried out in vitro cytotoxicity against a range of cell lines using the lactate dehydrogenase assay. They showed that coated discs 'did not exert any significant cytotoxicity.'

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Silver–polysaccharide nanocomposite antimicrobial coatings for methacrylic thermosets. Br Dent J 211, 423 (2011).

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