Virtually all patients with spinal cord injury (SCI) develop neurogenic lower urinary tract dysfunction (NLUTD). The primary goal of bladder management in patients with NLUTD as a result of suprasacral SCI is to achieve low urine storage pressure1 in order to protect renal function.

Irrespective of the method chosen for bladder management, the risk for urinary tract infection (UTI) is elevated in these persons. In men with NLUTD due to SCI, especially epididymo-orchitis is a common complication, which is found in up to 38.5% of the patients.2 If epididymo-orchitis is complicated by abscess formation, orchiectomy or epididymectomy is the method of choice.3 However, patients try to avoid ablative genital surgery whenever possible. We present the case of a multimodal approach of an organ-sparing treatment of an epididymal abscess.

Case report

In January 2014, a 35-year-old male patient with a traumatic complete tetraplegia below C6 since 2001, American Spinal Injury Association impairment scale A, was referred to us owing to a swelling of the left testicle, fever and increased spasticity. He emptied his bladder by reflex voiding five times a day. Since 5 days, he took norfloxacin without clinical improvement, long-term medication with baclofen 3 × 10 mg.

On physical examination, the left testicle was tender and swollen; the scrotal skin was reddened and stretched. Ultrasound revealed a thickened epididymis with a large (1.4 × 1.3 cm) abscess (Figure 1), confirmed by Doppler ultrasound. Urinalysis demonstrated a UTI with enterobacteria, sensitive only to imipenem, norfloxacin and nitrofurantoin.

Figure 1
figure 1

Ultrasound of the left scrotum: large epididymal abscess.

Blood testing showed elevated leukocyte count (15.78 ml−1) and C-reactive protein (83 mg l−1).

Owing to the progressive inflammation despite norfloxacin treatment, intravenous antibiotic treatment with imipenem and local measures (cooling, immobilization) were initiated. As both the abscess and the blood parameters remained unchanged after 3 days, epididymectomy/orchiectomy was proposed, which was rejected by the patient. Therefore, we initiated homeopathic treatment with Hamamelis virginiana C30, three times daily for 4 days, followed by Hamamelis C 200 two times daily for another 5 days. Under homeopathic treatment, the abscess became significantly smaller within 3 days and the infection parameters were decreasing. After 4 days, the abscess was not visible any more (Figure 2); however, there was a fluid collection under the scrotal skin. Needle aspiration revealed pus, which was sterile on microbiological testing. The following day, the abscess was incised; microbiologic examination of the fluid confirmed no growth of bacteria. During surgery, no cavity in the epididymis could be detected. After 1 more week, the incision could be closed. Sonographic control demonstrated an intact testicle and epididymis.

Figure 2
figure 2

Ultrasound of the left scrotum under treatment, 5 days later.


To our knowledge, this is the first report of a successful organ-sparing treatment for an epididymal abscess in a patient with SCI. A similar case has recently been reported in a patient under immunosuppression.4 Generally, the risk to acquire an epididymitis is elevated in patients with SCI due to the NLUTD.2 The bacteria detected in the urine are usually the causative agents. The key to organ preservation is an early and intensive multimodal approach, including immobilization, cooling, long-term (at least 10 days) antibiotic treatment and low-pressure bladder drainage. In the case presented here, however, abscess formation progressed and serum infection parameters remained elevated although all mentioned measures were taken and the bacteria were susceptible to both antibiotics, which were applied for more than a week. After adjunctive homeopathic treatment, local findings improved and infection parameters returned to normal. The quick amelioration of both the clinical symptoms and the sonographic findings demonstrated that homeopathic treatment might have significantly aided in the recovery.

We used classical homeopathy. In brief, this term comprises that a single remedy was selected based on the totality of signs and symptoms of the individual patient.5 Thus, Hamamelis virginiana cannot be regarded as a general remedy for epididymal abscess formation, but the particular symptoms of the individual patients have to be taken into consideration.


In persons with SCI suffering from epididymo-orchitis, an organ-preserving approach may be considered even in severe cases. Homeopathic treatment might have been a valuable adjunctive treatment in the mentioned case. Therefore, prospective studies are needed to further elucidate the future opportunities and limitations of classical homeopathy as an adjunct in the treatment of UTI.