Abstract
A group of 21 complete spinal cord injury patients, beyond the phase of spinal shock, were given a treatment of cisapride at random, 10 mg four times a day for 4 weeks. Cystometry was performed first before the start and during the following 4 weeks. No statistically significant difference could be found in the urodynamic parameters between the two groups at the first cystometry. No statistically significant change of the urodynamic parameters could be demonstrated with the treatment, although a non-statistically significant bladder stimulating effect was present in a majority of the patients in the cisapride group.
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Barone J A, Jessen L M, Colaizzi J L, Bierman R H . Cisapride: a gastro-intestinal prokinetic drug. Ann Pharmacother 1994; 28: 488–500.
Binnie N R, Creasey G H, Edmond P, Smith A . The action of cisapride on the chronic constipation of paraplegia. Paraplegia 1988; 26: 151–158.
Abrams P, Blaivas J G, Stanton S L, Andersen J T . The standardization of terminology of lower urinary tract function recommended by the International Continence Society. Int Urogynecol 7 1990; 1: 45–58.
Hanson P, Soler J M . Effet du cisapride sur les vessies neuro-logiques. Medica Physica 1989; 12: 81–88.
De Groat G H, De Pagter G F . Effects of cisapride on constipation due to a neurological lesion. Paraplegia 1988; 26: 159–161.
Etienne M, Verlinden M, Brassinne A . Treatment with cisapride of the gastro-intestinal and urological sequelae of spinal cord transection: case report. Paraplegia 1988; 26: 162–164.
Carone R, Vercelli D, Bertapelle P . Effects of cisapride on anorectal and vesico-urethral function in spinal cord injured patients. Paraplegia 1993; 31: 125–127.
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Wyndaele, J., Kerrebroeck, P. The effects of 4 weeks treatment with cisapride on cystometric parameters in spinal cord injury patients. A double-blind, placebo controlled study. Spinal Cord 33, 625–627 (1995). https://doi.org/10.1038/sc.1995.132
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DOI: https://doi.org/10.1038/sc.1995.132
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